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Joris Deelen
Joris Deelen
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Defining the role of common variation in the genomic and biological architecture of adult human height
AR Wood, T Esko, J Yang, S Vedantam, TH Pers, S Gustafsson, AY Chu, ...
Nature genetics 46 (11), 1173-1186, 2014
20892014
New genetic loci link adipose and insulin biology to body fat distribution
D Shungin, TW Winkler, DC Croteau-Chonka, T Ferreira, AE Locke, ...
Nature 518 (7538), 187-196, 2015
15832015
Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits
E Evangelou, HR Warren, D Mosen-Ansorena, B Mifsud, R Pazoki, H Gao, ...
Nature genetics 50 (10), 1412-1425, 2018
11312018
Identification of seven loci affecting mean telomere length and their association with disease
V Codd, CP Nelson, E Albrecht, M Mangino, J Deelen, JL Buxton, ...
Nature genetics 45 (4), 422-427, 2013
9612013
Facing up to the global challenges of ageing
L Partridge, J Deelen, PE Slagboom
Nature 561 (7721), 45-56, 2018
9372018
Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA
J Kettunen, A Demirkan, P Würtz, HHM Draisma, T Haller, R Rawal, ...
Nature communications 7 (1), 11122, 2016
6152016
Meta-analysis of telomere length in 19 713 subjects reveals high heritability, stronger maternal inheritance and a paternal age effect
L Broer, V Codd, DR Nyholt, J Deelen, M Mangino, G Willemsen, ...
European journal of human genetics 21 (10), 1163-1168, 2013
4932013
Disease variants alter transcription factor levels and methylation of their binding sites
MJ Bonder, R Luijk, DV Zhernakova, M Moed, P Deelen, M Vermaat, ...
Nature genetics 49 (1), 131-138, 2017
4432017
Identification of context-dependent expression quantitative trait loci in whole blood
DV Zhernakova, P Deelen, M Vermaat, M Van Iterson, M Van Galen, ...
Nature genetics 49 (1), 139-145, 2017
4402017
Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels
X Jiang, PF O’Reilly, H Aschard, YH Hsu, JB Richards, J Dupuis, ...
Nature communications 9 (1), 260, 2018
3712018
The impact of low-frequency and rare variants on lipid levels
I Surakka, M Horikoshi, R Mägi, AP Sarin, A Mahajan, V Lagou, L Marullo, ...
Nature genetics 47 (6), 589-597, 2015
3572015
Genome analyses of> 200,000 individuals identify 58 loci for chronic inflammation and highlight pathways that link inflammation and complex disorders
S Ligthart, A Vaez, U Võsa, MG Stathopoulou, PS De Vries, BP Prins, ...
The American Journal of Human Genetics 103 (5), 691-706, 2018
3502018
Genome‐wide association study identifies a single major locus contributing to survival into old age; the APOE locus revisited
J Deelen, M Beekman, HW Uh, Q Helmer, M Kuningas, L Christiansen, ...
Aging cell 10 (4), 686-698, 2011
3182011
GWAS of Longevity in CHARGE Consortium Confirms APOE and FOXO3 Candidacy
L Broer, AS Buchman, J Deelen, DS Evans, JD Faul, KL Lunetta, ...
Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences …, 2015
2812015
Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age
J Deelen, M Beekman, HW Uh, L Broer, KL Ayers, Q Tan, Y Kamatani, ...
Human molecular genetics 23 (16), 4420-4432, 2014
2802014
A meta-analysis of genome-wide association studies identifies multiple longevity genes
J Deelen, DS Evans, DE Arking, N Tesi, M Nygaard, X Liu, MK Wojczynski, ...
Nature communications 10 (1), 3669, 2019
2532019
A meta-analysis of thyroid-related traits reveals novel loci and gender-specific differences in the regulation of thyroid function
E Porcu, M Medici, G Pistis, CB Volpato, SG Wilson, AR Cappola, SD Bos, ...
PLoS genetics 9 (2), e1003266, 2013
2512013
A metabolic profile of all-cause mortality risk identified in an observational study of 44,168 individuals
J Deelen, J Kettunen, K Fischer, A van Der Spek, S Trompet, ...
Nature communications 10 (1), 3346, 2019
2322019
Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation
A Teumer, L Chaker, S Groeneweg, Y Li, C Di Munno, C Barbieri, ...
Nature communications 9 (1), 4455, 2018
2132018
Genome‐wide linkage analysis for human longevity: Genetics of Healthy Aging Study
M Beekman, H Blanché, M Perola, A Hervonen, V Bezrukov, E Sikora, ...
Aging cell 12 (2), 184-193, 2013
2082013
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Artikelen 1–20