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Khurum Khan
Khurum Khan
University College London NHS Foundation Trust
Adresse e-mail validée de nhs.net
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Patient-derived organoids model treatment response of metastatic gastrointestinal cancers
G Vlachogiannis, S Hedayat, A Vatsiou, Y Jamin, J Fernández-Mateos, ...
Science 359 (6378), 920-926, 2018
14732018
Neoadjuvant FOLFIRINOX in patients with borderline resectable pancreatic cancer: a systematic review and patient-level meta-analysis
QP Janssen, S Buettner, M Suker, BR Beumer, P Addeo, P Bachellier, ...
JNCI: Journal of the National Cancer Institute 111 (8), 782-794, 2019
2892019
Targeting the PI3K-AKT-mTOR signaling network in cancer
KH Khan, TA Yap, L Yan, D Cunningham
Chinese journal of cancer 32 (5), 253, 2013
2282013
Longitudinal liquid biopsy and mathematical modeling of clonal evolution forecast time to treatment failure in the PROSPECT-C phase II colorectal cancer clinical trial
KH Khan, D Cunningham, B Werner, G Vlachogiannis, I Spiteri, T Heide, ...
Cancer discovery 8 (10), 1270-1285, 2018
2092018
Genomic and transcriptomic determinants of therapy resistance and immune landscape evolution during anti-EGFR treatment in colorectal cancer
A Woolston, K Khan, G Spain, LJ Barber, B Griffiths, R Gonzalez-Exposito, ...
Cancer cell 36 (1), 35-50. e9, 2019
2042019
Cancer therapeutics: Targeting the apoptotic pathway
KH Khan, M Blanco-Codesido, LR Molife
Critical reviews in oncology/hematology 90 (3), 200-219, 2014
1862014
Antitumor Activity in RAS-Driven Tumors by Blocking AKT and MEK
AW Tolcher, K Khan, M Ong, U Banerji, V Papadimitrakopoulou, ...
Clinical Cancer Research 21 (4), 739-748, 2015
1412015
Anal cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up☆
S Rao, MG Guren, K Khan, G Brown, AG Renehan, SE Steigen, ...
Annals of Oncology 32 (9), 1087-1100, 2021
1222021
MIR21 drives resistance to heat shock protein 90 inhibition in cholangiocarcinoma
A Lampis, P Carotenuto, G Vlachogiannis, L Cascione, S Hedayat, ...
Gastroenterology 154 (4), 1066-1079. e5, 2018
1112018
Challenges in the treatment of gastric cancer in the older patient
N Joharatnam-Hogan, KK Shiu, K Khan
Cancer treatment reviews 85, 101980, 2020
952020
CEA expression heterogeneity and plasticity confer resistance to the CEA-targeting bispecific immunotherapy antibody cibisatamab (CEA-TCB) in patient-derived colorectal cancer …
R Gonzalez-Exposito, M Semiannikova, B Griffiths, K Khan, LJ Barber, ...
Journal for immunotherapy of cancer 7, 1-14, 2019
782019
Colorectal cancer with liver metastases: neoadjuvant chemotherapy, surgical resection first or palliation alone?
K Khan, A Wale, G Brown, I Chau
World Journal of Gastroenterology: WJG 20 (35), 12391, 2014
742014
Functional imaging and circulating biomarkers of response to regorafenib in treatment-refractory metastatic colorectal cancer patients in a prospective phase II study
K Khan, M Rata, D Cunningham, DM Koh, N Tunariu, JC Hahne, ...
Gut 67 (8), 1484-1492, 2018
692018
FOLFIRINOX for locally advanced or metastatic pancreatic ductal adenocarcinoma: the Royal Marsden experience
SY Moorcraft, K Khan, C Peckitt, D Watkins, S Rao, D Cunningham, ...
Clinical colorectal cancer 13 (4), 232-238, 2014
692014
Hyperglycemia and Phosphatidylinositol 3-Kinase/Protein Kinase B/Mammalian Target of Rapamycin (PI3K/AKT/mTOR) Inhibitors in Phase I Trials: Incidence, Predictive Factors, and …
MLR Khan KH, Wong M, Rihawi K, Bodla S, Morganstein D, Banerji U
The Oncologist, 2016
632016
Targeting EGFR pathway in metastatic colorectal cancer-tumour heterogeniety and convergent evolution
K Khan, N Valeri, C Dearman, S Rao, D Watkins, N Starling, I Chau, ...
Critical reviews in oncology/hematology 143, 153-163, 2019
582019
Immunotherapy in gastrointestinal cancer: The current scenario and future perspectives
M Abdul-Latif, K Townsend, C Dearman, KK Shiu, K Khan
Cancer Treatment Reviews 88, 102030, 2020
532020
Phase I trial of cyclophosphamide as an immune modulator for optimizing oncolytic reovirus delivery to solid tumors
SJ Roulstone V, Khan K, Pandha HS, Rudman S, Coffey M, Gill GM, Melcher AA ...
Clin Cancer Res., 2014
51*2014
<? covid19?> Outcomes of the 2019 novel coronavirus in patients with or without a history of cancer: a multi-centre North London experience
N Joharatnam-Hogan, D Hochhauser, KK Shiu, H Rush, V Crolley, ...
Therapeutic advances in medical oncology 12, 1758835920956803, 2020
412020
miR-21 expression and clinical outcome in locally advanced pancreatic cancer: exploratory analysis of the pancreatic cancer Erbitux, radiotherapy and UFT (PERU) trial
K Khan, D Cunningham, C Peckitt, S Barton, D Tait, M Hawkins, ...
Oncotarget 7 (11), 12672, 2016
412016
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