Miles Pufall
Miles Pufall
Associate Professor of Biochemistry, University of Iowa
Verified email at uiowa.edu - Homepage
Title
Cited by
Cited by
Year
DNA binding site sequence directs glucocorticoid receptor structure and activity
SH Meijsing, MA Pufall, AY So, DL Bates, L Chen, KR Yamamoto
Science 324 (5925), 407-410, 2009
6842009
Reversible targeting of noncatalytic cysteines with chemically tuned electrophiles
IM Serafimova, MA Pufall, S Krishnan, K Duda, MS Cohen, RL Maglathlin, ...
Nature chemical biology 8 (5), 471-476, 2012
3882012
Variable control of Ets-1 DNA binding by multiple phosphates in an unstructured region
MA Pufall, GM Lee, ML Nelson, HS Kang, A Velyvis, LE Kay, LP McIntosh, ...
science 309 (5731), 142-145, 2005
2532005
Autoinhibitory domains: modular effectors of cellular regulation
MA Pufall, BJ Graves
Annual review of cell and developmental biology 18 (1), 421-462, 2002
2482002
The glucocorticoid receptor dimer interface allosterically transmits sequence-specific DNA signals
LC Watson, KM Kuchenbecker, BJ Schiller, JD Gross, MA Pufall, ...
Nature structural & molecular biology 20 (7), 876-883, 2013
1492013
Metabolic gatekeeper function of B-lymphoid transcription factors
LN Chan, Z Chen, D Braas, JW Lee, G Xiao, H Geng, KN Cosgun, C Hurtz, ...
Nature 542 (7642), 479-483, 2017
1232017
Glucocorticoids and cancer
MA Pufall
Glucocorticoid Signaling, 315-333, 2015
1192015
Transcriptional Regulation of Human Dual Specificity Protein Phosphatase 1 (DUSP1) Gene by Glucocorticoids
LE Shipp, JV Lee, CY Yu, M Pufall, P Zhang, DK Scott, JC Wang
PLoS One 5 (10), e13754, 2010
1112010
Structural analysis of the autoinhibition of Ets-1 and its role in protein partnerships
CW Garvie, MA Pufall, BJ Graves, C Wolberger
Journal of Biological Chemistry 277 (47), 45529-45536, 2002
1102002
The structural and dynamic basis of Ets-1 DNA binding autoinhibition
GM Lee, LW Donaldson, MA Pufall, HS Kang, I Pot, BJ Graves, ...
Journal of Biological Chemistry 280 (8), 7088-7099, 2005
1092005
The affinity of Ets-1 for DNA is modulated by phosphorylation through transient interactions of an unstructured region
GM Lee, MA Pufall, CA Meeker, HS Kang, BJ Graves, LP McIntosh
Journal of molecular biology 382 (4), 1014-1030, 2008
712008
JUNB is a key transcriptional modulator of macrophage activation
MF Fontana, A Baccarella, N Pancholi, MA Pufall, RH De’Broski, CC Kim
The Journal of Immunology 194 (1), 177-186, 2015
572015
A naturally occuring insertion of a single amino acid rewires transcriptional regulation by glucocorticoid receptor isoforms
M Thomas-Chollier, LC Watson, SB Cooper, MA Pufall, JS Liu, K Borzym, ...
Proceedings of the National Academy of Sciences 110 (44), 17826-17831, 2013
572013
EC coupling structural protein junctophilin-2 encodes a stress-adaptive transcription regulator
A Guo, Y Wang, B Chen, Y Wang, J Yuan, L Zhang, D Hall, J Wu, Y Shi, ...
Science 362 (6421), 2018
462018
Spermine oxidase maintains basal skeletal muscle gene expression and fiber size and is strongly repressed by conditions that cause skeletal muscle atrophy
KS Bongers, DK Fox, SD Kunkel, LV Stebounova, DJ Murry, MA Pufall, ...
American Journal of Physiology-Endocrinology and Metabolism 308 (2), E144-E158, 2015
382015
Suppression of B-cell development genes is key to glucocorticoid efficacy in treatment of acute lymphoblastic leukemia
KA Kruth, M Fang, DN Shelton, O Abu-Halawa, R Mahling, H Yang, ...
Blood, The Journal of the American Society of Hematology 129 (22), 3000-3008, 2017
372017
Response element composition governs correlations between binding site affinity and transcription in glucocorticoid receptor feed-forward loops
SK Sasse, Z Zuo, V Kadiyala, L Zhang, MA Pufall, MK Jain, TL Phang, ...
Journal of Biological Chemistry 290 (32), 19756-19769, 2015
272015
DNA mismatches reveal conformational penalties in protein–DNA recognition
A Afek, H Shi, A Rangadurai, H Sahay, A Senitzki, S Xhani, M Fang, ...
Nature 587 (7833), 291-296, 2020
252020
SelexGLM differentiates androgen and glucocorticoid receptor DNA-binding preference over an extended binding site
L Zhang, GD Martini, HT Rube, JF Kribelbauer, C Rastogi, VD FitzPatrick, ...
Genome research 28 (1), 111-121, 2018
242018
Ets-1 flips for new partner Pax-5
MA Pufall, BJ Graves
Structure 10 (1), 11-14, 2002
232002
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