Miles Pufall
Miles Pufall
Associate Professor of Biochemistry, University of Iowa
Verified email at - Homepage
Cited by
Cited by
DNA binding site sequence directs glucocorticoid receptor structure and activity
SH Meijsing, MA Pufall, AY So, DL Bates, L Chen, KR Yamamoto
Science 324 (5925), 407-410, 2009
Reversible targeting of noncatalytic cysteines with chemically tuned electrophiles
IM Serafimova, MA Pufall, S Krishnan, K Duda, MS Cohen, RL Maglathlin, ...
Nature chemical biology 8 (5), 471-476, 2012
Variable control of Ets-1 DNA binding by multiple phosphates in an unstructured region
MA Pufall, GM Lee, ML Nelson, HS Kang, A Velyvis, LE Kay, LP McIntosh, ...
science 309 (5731), 142-145, 2005
Autoinhibitory domains: modular effectors of cellular regulation
MA Pufall, BJ Graves
Annual review of cell and developmental biology 18 (1), 421-462, 2002
Metabolic gatekeeper function of B-lymphoid transcription factors
LN Chan, Z Chen, D Braas, JW Lee, G Xiao, H Geng, KN Cosgun, C Hurtz, ...
Nature 542 (7642), 479-483, 2017
Glucocorticoids and cancer
MA Pufall
Glucocorticoid Signaling: From Molecules to Mice to Man, 315-333, 2015
The glucocorticoid receptor dimer interface allosterically transmits sequence-specific DNA signals
LC Watson, KM Kuchenbecker, BJ Schiller, JD Gross, MA Pufall, ...
Nature structural & molecular biology 20 (7), 876-883, 2013
Transcriptional Regulation of Human Dual Specificity Protein Phosphatase 1 (DUSP1) Gene by Glucocorticoids
LE Shipp, JV Lee, CY Yu, M Pufall, P Zhang, DK Scott, JC Wang
PLoS One 5 (10), e13754, 2010
Structural analysis of the autoinhibition of Ets-1 and its role in protein partnerships
CW Garvie, MA Pufall, BJ Graves, C Wolberger
Journal of Biological Chemistry 277 (47), 45529-45536, 2002
The structural and dynamic basis of Ets-1 DNA binding autoinhibition
GM Lee, LW Donaldson, MA Pufall, HS Kang, I Pot, BJ Graves, ...
Journal of Biological Chemistry 280 (8), 7088-7099, 2005
JUNB is a key transcriptional modulator of macrophage activation
MF Fontana, A Baccarella, N Pancholi, MA Pufall, DBR Herbert, CC Kim
The Journal of Immunology 194 (1), 177-186, 2015
EC coupling structural protein junctophilin-2 encodes a stress-adaptive transcription regulator
A Guo, Y Wang, B Chen, Y Wang, J Yuan, L Zhang, D Hall, J Wu, Y Shi, ...
Science 362 (6421), eaan3303, 2018
DNA mismatches reveal conformational penalties in protein–DNA recognition
A Afek, H Shi, A Rangadurai, H Sahay, A Senitzki, S Xhani, M Fang, ...
Nature 587 (7833), 291-296, 2020
The affinity of Ets-1 for DNA is modulated by phosphorylation through transient interactions of an unstructured region
GM Lee, MA Pufall, CA Meeker, HS Kang, BJ Graves, LP McIntosh
Journal of molecular biology 382 (4), 1014-1030, 2008
A naturally occuring insertion of a single amino acid rewires transcriptional regulation by glucocorticoid receptor isoforms
M Thomas-Chollier, LC Watson, SB Cooper, MA Pufall, JS Liu, K Borzym, ...
Proceedings of the National Academy of Sciences 110 (44), 17826-17831, 2013
Suppression of B-cell development genes is key to glucocorticoid efficacy in treatment of acute lymphoblastic leukemia
KA Kruth, M Fang, DN Shelton, O Abu-Halawa, R Mahling, H Yang, ...
Blood, The Journal of the American Society of Hematology 129 (22), 3000-3008, 2017
Spermine oxidase maintains basal skeletal muscle gene expression and fiber size and is strongly repressed by conditions that cause skeletal muscle atrophy
KS Bongers, DK Fox, SD Kunkel, LV Stebounova, DJ Murry, MA Pufall, ...
American Journal of Physiology-Endocrinology and Metabolism 308 (2), E144-E158, 2015
Response element composition governs correlations between binding site affinity and transcription in glucocorticoid receptor feed-forward loops
SK Sasse, Z Zuo, V Kadiyala, L Zhang, MA Pufall, MK Jain, TL Phang, ...
Journal of Biological Chemistry 290 (32), 19756-19769, 2015
Nascent transcript analysis of glucocorticoid crosstalk with TNF defines primary and cooperative inflammatory repression
SK Sasse, M Gruca, MA Allen, V Kadiyala, T Song, F Gally, A Gupta, ...
Genome research 29 (11), 1753-1765, 2019
SelexGLM differentiates androgen and glucocorticoid receptor DNA-binding preference over an extended binding site
L Zhang, GD Martini, HT Rube, JF Kribelbauer, C Rastogi, VD FitzPatrick, ...
Genome research 28 (1), 111-121, 2018
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