| The short-chain fatty acid pentanoate suppresses autoimmunity by modulating the metabolic-epigenetic crosstalk in lymphocytes M Luu, S Pautz, V Kohl, R Singh, R Romero, S Lucas, J Hofmann, ... Nature communications 10 (1), 760, 2019 | 319 | 2019 |
| The unique molecular and cellular microenvironment of ovarian cancer T Worzfeld, E Pogge von Strandmann, M Huber, T Adhikary, U Wagner, ... Frontiers in oncology 7, 24, 2017 | 246 | 2017 |
| Regulation of the effector function of CD8+ T cells by gut microbiota-derived metabolite butyrate M Luu, K Weigand, F Wedi, C Breidenbend, H Leister, S Pautz, T Adhikary, ... Scientific reports 8 (1), 14430, 2018 | 218 | 2018 |
| 15-hydroxyeicosatetraenoic acid is a preferential peroxisome proliferator-activated receptor β/δ agonist S Naruhn, W Meissner, T Adhikary, K Kaddatz, T Klein, B Watzer, ... Molecular pharmacology 77 (2), 171-184, 2010 | 117 | 2010 |
| Genomewide analyses define different modes of transcriptional regulation by peroxisome proliferator-activated receptor-β/δ (PPARβ/δ) T Adhikary, K Kaddatz, F Finkernagel, A Schönbauer, W Meissner, ... PloS one 6 (1), e16344, 2011 | 111 | 2011 |
| A transcriptome-based global map of signaling pathways in the ovarian cancer microenvironment associated with clinical outcome S Reinartz, F Finkernagel, T Adhikary, V Rohnalter, T Schumann, ... Genome biology 17, 1-22, 2016 | 99 | 2016 |
| Inverse PPARβ/δ agonists suppress oncogenic signaling to the ANGPTL4 gene and inhibit cancer cell invasion T Adhikary, DT Brandt, K Kaddatz, J Stockert, S Naruhn, W Meissner, ... Oncogene 32 (44), 5241-5252, 2013 | 99 | 2013 |
| The transcriptional PPARβ/δ network in human macrophages defines a unique agonist-induced activation state T Adhikary, A Wortmann, T Schumann, F Finkernagel, S Lieber, K Roth, ... Nucleic acids research 43 (10), 5033-5051, 2015 | 98 | 2015 |
| Deregulation of PPARβ/δ target genes in tumor-associated macrophages by fatty acid ligands in the ovarian cancer microenvironment T Schumann, T Adhikary, A Wortmann, F Finkernagel, S Lieber, ... Oncotarget 6 (15), 13416, 2015 | 95 | 2015 |
| The transcriptional signature of human ovarian carcinoma macrophages is associated with extracellular matrix reorganization F Finkernagel, S Reinartz, S Lieber, T Adhikary, A Wortmann, N Hoffmann, ... Oncotarget 7 (46), 75339, 2016 | 91 | 2016 |
| A multi-stage process including transient polyploidization and EMT precedes the emergence of chemoresistent ovarian carcinoma cells with a dedifferentiated and pro-inflammatory … V Rohnalter, K Roth, F Finkernagel, T Adhikary, J Obert, K Dorzweiler, ... Oncotarget 6 (37), 40005, 2015 | 90 | 2015 |
| Transcriptional Profiling Identifies Functional Interactions of TGFβ and PPARβ/δ Signaling: SYNERGISTIC INDUCTION OF ANGPTL4 TRANSCRIPTION K Kaddatz, T Adhikary, F Finkernagel, W Meissner, S MÜller-BrÜsselbach, ... Journal of Biological Chemistry 285 (38), 29469-29479, 2010 | 90 | 2010 |
| Proteotranscriptomics reveal signaling networks in the ovarian cancer microenvironment T Worzfeld, F Finkernagel, S Reinartz, A Konzer, T Adhikary, A Nist, ... Molecular & Cellular Proteomics 17 (2), 270-289, 2018 | 61 | 2018 |
| (Z)-2-(2-Bromophenyl)-3-{[4-(1-methyl-piperazine)amino]phenyl}acrylonitrile (DG172): An Orally Bioavailable PPARβ/δ-Selective Ligand with Inverse Agonistic … S Lieber, F Scheer, W Meissner, S Naruhn, T Adhikary, ... Journal of medicinal chemistry 55 (6), 2858-2868, 2012 | 60 | 2012 |
| High-affinity peroxisome proliferator-activated receptor β/δ-specific ligands with pure antagonistic or inverse agonistic properties S Naruhn, PM Toth, T Adhikary, K Kaddatz, V Pape, S Dörr, G Klebe, ... Molecular pharmacology 80 (5), 828-838, 2011 | 58 | 2011 |
| Interferon signaling in ascites-associated macrophages is linked to a favorable clinical outcome in a subgroup of ovarian carcinoma patients T Adhikary, A Wortmann, F Finkernagel, S Lieber, A Nist, T Stiewe, ... BMC genomics 18, 1-14, 2017 | 57 | 2017 |
| Reverse crosstalk of TGFβ and PPARβ/δ signaling identified by transcriptional profiling J Stockert, T Adhikary, K Kaddatz, F Finkernagel, W Meissner, ... Nucleic acids research 39 (1), 119-131, 2011 | 43 | 2011 |
| Lysophosphatidylcholines activate PPARδ and protect human skeletal muscle cells from lipotoxicity C Klingler, X Zhao, T Adhikary, J Li, G Xu, HU Häring, E Schleicher, ... Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2016 | 41 | 2016 |
| Lactate induces metabolic and epigenetic reprogramming of pro‐inflammatory Th17 cells A Lopez Krol, HP Nehring, FF Krause, A Wempe, H Raifer, A Nist, ... EMBO reports 23 (12), e54685, 2022 | 23 | 2022 |
| Epigenome-wide DNA methylation profiling in Progressive Supranuclear Palsy reveals major changes at DLX1 A Weber, SC Schwarz, J Tost, D Trümbach, P Winter, F Busato, P Tacik, ... Nature communications 9 (1), 2929, 2018 | 21 | 2018 |
Florian FinkernagelInstitute for molecular biology and tumor researchGeverifieerd e-mailadres voor imt.uni-marburg.de
