Till Adhikary
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Geciteerd door
The unique molecular and cellular microenvironment of ovarian cancer
T Worzfeld, E Pogge von Strandmann, M Huber, T Adhikary, U Wagner, ...
Frontiers in oncology 7, 24, 2017
Genomewide analyses define different modes of transcriptional regulation by peroxisome proliferator-activated receptor-β/δ (PPARβ/δ)
T Adhikary, K Kaddatz, F Finkernagel, A Schönbauer, W Meissner, ...
PloS one 6 (1), e16344, 2011
15-hydroxyeicosatetraenoic acid is a preferential peroxisome proliferator-activated receptor β/δ agonist
S Naruhn, W Meissner, T Adhikary, K Kaddatz, T Klein, B Watzer, ...
Molecular pharmacology 77 (2), 171-184, 2010
The short-chain fatty acid pentanoate suppresses autoimmunity by modulating the metabolic-epigenetic crosstalk in lymphocytes
M Luu, S Pautz, V Kohl, R Singh, R Romero, S Lucas, J Hofmann, ...
Nature communications 10 (1), 1-12, 2019
Regulation of the effector function of CD8+ T cells by gut microbiota-derived metabolite butyrate
M Luu, K Weigand, F Wedi, C Breidenbend, H Leister, S Pautz, T Adhikary, ...
Scientific reports 8 (1), 1-10, 2018
Inverse PPARβ/δ agonists suppress oncogenic signaling to the ANGPTL4 gene and inhibit cancer cell invasion
T Adhikary, DT Brandt, K Kaddatz, J Stockert, S Naruhn, W Meissner, ...
Oncogene 32 (44), 5241-5252, 2013
Transcriptional Profiling Identifies Functional Interactions of TGFβ and PPARβ/δ Signaling: SYNERGISTIC INDUCTION OF ANGPTL4 TRANSCRIPTION [S]
K Kaddatz, T Adhikary, F Finkernagel, W Meissner, S Müller-Brüsselbach, ...
Journal of Biological Chemistry 285 (38), 29469-29479, 2010
A transcriptome-based global map of signaling pathways in the ovarian cancer microenvironment associated with clinical outcome
S Reinartz, F Finkernagel, T Adhikary, V Rohnalter, T Schumann, ...
Genome biology 17 (1), 1-22, 2016
Deregulation of PPARβ/δ target genes in tumor-associated macrophages by fatty acid ligands in the ovarian cancer microenvironment
T Schumann, T Adhikary, A Wortmann, F Finkernagel, S Lieber, ...
Oncotarget 6 (15), 13416, 2015
The transcriptional signature of human ovarian carcinoma macrophages is associated with extracellular matrix reorganization
F Finkernagel, S Reinartz, S Lieber, T Adhikary, A Wortmann, N Hoffmann, ...
Oncotarget 7 (46), 75339, 2016
The transcriptional PPARβ/δ network in human macrophages defines a unique agonist-induced activation state
T Adhikary, A Wortmann, T Schumann, F Finkernagel, S Lieber, K Roth, ...
Nucleic acids research 43 (10), 5033-5051, 2015
A multi-stage process including transient polyploidization and EMT precedes the emergence of chemoresistent ovarian carcinoma cells with a dedifferentiated and pro-inflammatory …
V Rohnalter, K Roth, F Finkernagel, T Adhikary, J Obert, K Dorzweiler, ...
Oncotarget 6 (37), 40005, 2015
High-affinity peroxisome proliferator-activated receptor β/δ-specific ligands with pure antagonistic or inverse agonistic properties
S Naruhn, PM Toth, T Adhikary, K Kaddatz, V Pape, S Dörr, G Klebe, ...
Molecular pharmacology 80 (5), 828-838, 2011
(Z)-2-(2-Bromophenyl)-3-{[4-(1-methyl-piperazine)amino]phenyl}acrylonitrile (DG172): An Orally Bioavailable PPARβ/δ-Selective Ligand with Inverse Agonistic …
S Lieber, F Scheer, W Meissner, S Naruhn, T Adhikary, ...
Journal of medicinal chemistry 55 (6), 2858-2868, 2012
Reverse crosstalk of TGFβ and PPARβ/δ signaling identified by transcriptional profiling
J Stockert, T Adhikary, K Kaddatz, F Finkernagel, W Meissner, ...
Nucleic acids research 39 (1), 119-131, 2011
Proteotranscriptomics reveal signaling networks in the ovarian cancer microenvironment
T Worzfeld, F Finkernagel, S Reinartz, A Konzer, T Adhikary, A Nist, ...
Molecular & Cellular Proteomics 17 (2), 270-289, 2018
Interferon signaling in ascites-associated macrophages is linked to a favorable clinical outcome in a subgroup of ovarian carcinoma patients
T Adhikary, A Wortmann, F Finkernagel, S Lieber, A Nist, T Stiewe, ...
BMC genomics 18 (1), 1-14, 2017
Lysophosphatidylcholines activate PPARδ and protect human skeletal muscle cells from lipotoxicity
C Klingler, X Zhao, T Adhikary, J Li, G Xu, HU Häring, E Schleicher, ...
Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2016
Design and Synthesis of Highly Active Peroxisome Proliferator‐Activated Receptor (PPAR) β/δ Inverse Agonists with Prolonged Cellular Activity
PM Toth, S Lieber, FM Scheer, T Schumann, Y Schober, WA Nockher, ...
ChemMedChem 11 (5), 488-496, 2016
Epigenome-wide DNA methylation profiling in Progressive Supranuclear Palsy reveals major changes at DLX1
A Weber, SC Schwarz, J Tost, D Trümbach, P Winter, F Busato, P Tacik, ...
Nature communications 9 (1), 1-12, 2018
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