| Risks of breast, ovarian, and contralateral breast cancer for BRCA1 and BRCA2 mutation carriers KB Kuchenbaecker, JL Hopper, DR Barnes, KA Phillips, TM Mooij, ... Jama 317 (23), 2402-2416, 2017 | 2678 | 2017 |
| A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance AK Manning, MF Hivert, RA Scott, JL Grimsby, N Bouatia-Naji, H Chen, ... Nature genetics 44 (6), 659-669, 2012 | 911* | 2012 |
| Common variants at 10 genomic loci influence hemoglobin A1C levels via glycemic and nonglycemic pathways N Soranzo, S Sanna, E Wheeler, C Gieger, D Radke, J Dupuis, ... Diabetes 59 (12), 3229-3239, 2010 | 478 | 2010 |
| Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes RJ Strawbridge, J Dupuis, I Prokopenko, A Barker, E Ahlqvist, D Rybin, ... Diabetes 60 (10), 2624-2634, 2011 | 451 | 2011 |
| Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer RL Milne, KB Kuchenbaecker, K Michailidou, J Beesley, S Kar, ... Nature genetics 49 (12), 1767-1778, 2017 | 351 | 2017 |
| Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension P Surendran, F Drenos, R Young, H Warren, JP Cook, AK Manning, ... Nature genetics 48 (10), 1151-1161, 2016 | 315 | 2016 |
| Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses H Zhang, TU Ahearn, J Lecarpentier, D Barnes, J Beesley, G Qi, X Jiang, ... Nature genetics 52 (6), 572-581, 2020 | 301 | 2020 |
| Fifteen new risk loci for coronary artery disease highlight arterial-wall-specific mechanisms JMM Howson, W Zhao, DR Barnes, WK Ho, R Young, DS Paul, LL Waite, ... Nature genetics 49 (7), 1113-1119, 2017 | 298 | 2017 |
| Exome Sequencing Identifies Rare Deleterious Mutations in DNA Repair Genes FANCC and BLM as Potential Breast Cancer Susceptibility Alleles ER Thompson, MA Doyle, GL Ryland, SM Rowley, DYH Choong, ... Public Library of Science 8 (9), e1002894, 2012 | 254 | 2012 |
| Functional variants at the 11q13 risk locus for breast cancer regulate cyclin D1 expression through long-range enhancers JD French, M Ghoussaini, SL Edwards, KB Meyer, K Michailidou, ... The American Journal of Human Genetics 92 (4), 489-503, 2013 | 253 | 2013 |
| Tumour risks and genotype–phenotype correlations associated with germline variants in succinate dehydrogenase subunit genes SDHB, SDHC and SDHD KA Andrews, DB Ascher, DEV Pires, DR Barnes, L Vialard, RT Casey, ... Journal of medical genetics 55 (6), 384-394, 2018 | 215 | 2018 |
| Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes L Fachal, H Aschard, J Beesley, DR Barnes, J Allen, S Kar, KA Pooley, ... Nature genetics 52 (1), 56-73, 2020 | 154 | 2020 |
| Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci AM Erzurumluoglu, M Liu, VE Jackson, DR Barnes, G Datta, ... Molecular psychiatry 25 (10), 2392-2409, 2020 | 124 | 2020 |
| Genome-wide association and transcriptome studies identify target genes and risk loci for breast cancer MA Ferreira, ER Gamazon, F Al-Ejeh, K Aittomäki, IL Andrulis, ... Nature communications 10 (1), 1741, 2019 | 121 | 2019 |
| No evidence for a causal link between uric acid and type 2 diabetes: a Mendelian randomisation approach R Pfister, D Barnes, R Luben, NG Forouhi, M Bochud, KT Khaw, ... Diabetologia 54, 2561-2569, 2011 | 116 | 2011 |
| Shared heritability and functional enrichment across six solid cancers X Jiang, HK Finucane, FR Schumacher, SL Schmit, JP Tyrer, Y Han, ... Nature communications 10 (1), 431, 2019 | 113 | 2019 |
| Polygenic risk scores and breast and epithelial ovarian cancer risks for carriers of BRCA1 and BRCA2 pathogenic variants DR Barnes, MA Rookus, L McGuffog, G Leslie, TM Mooij, J Dennis, ... Genetics in Medicine 22 (10), 1653-1666, 2020 | 101 | 2020 |
| Meta-analysis of genome wide association studies identifies genetic markers of late toxicity following radiotherapy for prostate cancer SL Kerns, L Dorling, L Fachal, S Bentzen, PDP Pharoah, DR Barnes, ... EBioMedicine 10, 150-163, 2016 | 91 | 2016 |
| Unravelling modifiers of breast and ovarian cancer risk for BRCA1 and BRCA2 mutation carriers: update on genetic modifiers DR Barnes, AC Antoniou Journal of internal medicine 271 (4), 331-343, 2012 | 77 | 2012 |
| Exome chip meta-analysis fine maps causal variants and elucidates the genetic architecture of rare coding variants in smoking and alcohol use DM Brazel, Y Jiang, JM Hughey, V Turcot, X Zhan, J Gong, C Batini, ... Biological psychiatry 85 (11), 946-955, 2019 | 71 | 2019 |
Prof. Antonis C. AntoniouProfessor of Cancer Risk Prediction, University of CambridgeVerified email at medschl.cam.ac.uk
