Comprehensive alpha, beta and delta cell transcriptomes reveal that ghrelin selectively activates delta cells and promotes somatostatin release from pancreatic islets MR DiGruccio, AM Mawla, CJ Donaldson, GM Noguchi, J Vaughan, ... Molecular metabolism 5 (7), 449-458, 2016 | 324 | 2016 |
NMR structure and peptide hormone binding site of the first extracellular domain of a type B1 G protein-coupled receptor CRR Grace, MH Perrin, MR DiGruccio, CL Miller, JE Rivier, WW Vale, ... Proceedings of the National Academy of Sciences 101 (35), 12836-12841, 2004 | 249 | 2004 |
Virgin beta cells persist throughout life at a neogenic niche within pancreatic islets T van der Meulen, AM Mawla, MR DiGruccio, MW Adams, V Nies, ... Cell metabolism 25 (4), 911-926. e6, 2017 | 209 | 2017 |
Potent and long-acting corticotropin releasing factor (CRF) receptor 2 selective peptide competitive antagonists J Rivier, J Gulyas, D Kirby, W Low, MH Perrin, K Kunitake, M DiGruccio, ... Journal of medicinal chemistry 45 (21), 4737-4747, 2002 | 190 | 2002 |
The abolishment of anesthesia-induced cognitive impairment by timely protection of mitochondria in the developing rat brain: the importance of free oxygen radicals and … A Boscolo, JA Starr, V Sanchez, N Lunardi, MR DiGruccio, C Ori, A Erisir, ... Neurobiology of disease 45 (3), 1031-1041, 2012 | 179 | 2012 |
Structure of the N-terminal domain of a type B1 G protein-coupled receptor in complex with a peptide ligand CRR Grace, MH Perrin, J Gulyas, MR DiGruccio, JP Cantle, JE Rivier, ... Proceedings of the National Academy of Sciences 104 (12), 4858-4863, 2007 | 160 | 2007 |
A soluble mouse brain splice variant of type 2α corticotropin-releasing factor (CRF) receptor binds ligands and modulates their activity AM Chen, MH Perrin, MR DiGruccio, JM Vaughan, BK Brar, CM Arias, ... Proceedings of the National Academy of Sciences 102 (7), 2620-2625, 2005 | 133 | 2005 |
Reversal of Neuropathic Pain in Diabetes by Targeting Glycosylation of Cav3.2 T-Type Calcium Channels P Orestes, HP Osuru, WE McIntire, MO Jacus, R Salajegheh, MM Jagodic, ... Diabetes 62 (11), 3828-3838, 2013 | 120 | 2013 |
General anesthesia causes epigenetic histone modulation of c-Fos and brain-derived neurotrophic factor, target genes important for neuronal development in the immature rat … L Dalla Massara, HP Osuru, A Oklopcic, D Milanovic, SM Joksimovic, ... Anesthesiology 124 (6), 1311-1327, 2016 | 79 | 2016 |
A soluble form of the first extracellular domain of mouse type 2β corticotropin-releasing factor receptor reveals differential ligand specificity MH Perrin, MR DiGruccio, SC Koerber, JE Rivier, KS Kunitake, DL Bain, ... Journal of Biological Chemistry 278 (18), 15595-15600, 2003 | 75 | 2003 |
Primary cilia control glucose homeostasis via islet paracrine interactions JW Hughes, JH Cho, HE Conway, MR DiGruccio, XW Ng, HF Roseman, ... Proceedings of the National Academy of Sciences 117 (16), 8912-8923, 2020 | 64 | 2020 |
Stressin1-A, a Potent Corticotropin Releasing Factor Receptor 1 (CRF1)-Selective Peptide Agonist J Rivier, J Gulyas, K Kunitake, M DiGruccio, JP Cantle, MH Perrin, ... Journal of medicinal chemistry 50 (7), 1668-1674, 2007 | 53 | 2007 |
Type 2 corticotropin-releasing factor receptor in the ventromedial nucleus of hypothalamus is critical in regulating feeding and lipid metabolism in white adipose tissue H Chao, M Digruccio, P Chen, C Li Endocrinology 153 (1), 166-176, 2012 | 50 | 2012 |
Free radical signalling underlies inhibition of CaV3.2 T‐type calcium channels by nitrous oxide in the pain pathway P Orestes, D Bojadzic, JH Lee, E Leach, R Salajegheh, MR DiGruccio, ... The Journal of physiology 589 (1), 135-148, 2011 | 48 | 2011 |
Inhibition of T-type calcium current in rat thalamocortical neurons by isoflurane VS Eckle, MR DiGruccio, VN Uebele, JJ Renger, SM Todorovic Neuropharmacology 63 (2), 266-273, 2012 | 39 | 2012 |
Hyperexcitability of rat thalamocortical networks after exposure to general anesthesia during brain development MR DiGruccio, S Joksimovic, PM Joksovic, N Lunardi, R Salajegheh, ... Journal of Neuroscience 35 (4), 1481-1492, 2015 | 37 | 2015 |
The role of T‐type calcium channels in the subiculum: to burst or not to burst? SM Joksimovic, P Eggan, Y Izumi, SL Joksimovic, V Tesic, RM Dietz, ... The Journal of physiology 595 (19), 6327-6348, 2017 | 32 | 2017 |
Inhibition of CaV3. 2 T-type calcium channels in peripheral sensory neurons contributes to analgesic properties of epipregnanolone C Ayoola, SM Hwang, SJ Hong, KE Rose, C Boyd, N Bozic, JY Park, ... Psychopharmacology 231, 3503-3515, 2014 | 26 | 2014 |
Distinct structural and functional roles of conserved residues in the first extracellular domain of receptors for corticotropin-releasing factor and related G-protein-coupled … MH Perrin, CRR Grace, MR DiGruccio, WH Fischer, SK Maji, JP Cantle, ... Journal of biological chemistry 282 (52), 37529-37536, 2007 | 21 | 2007 |
MALDI-MS analysis of peptides modified with photolabile arylazido groups W Low, J Kang, M DiGruccio, D Kirby, M Perrin, WH Fischer Journal of the American Society for Mass Spectrometry 15 (8), 1156-1160, 2004 | 19 | 2004 |