| Oxidative stress during acetaminophen hepatotoxicity: Sources, pathophysiological role and therapeutic potential K Du, A Ramachandran, H Jaeschke Redox biology 10, 148-156, 2016 | 460 | 2016 |
| Hedgehog-YAP signaling pathway regulates glutaminolysis to control activation of hepatic stellate cells K Du, J Hyun, RT Premont, SS Choi, GA Michelotti, M Swiderska-Syn, ... gastroenterology 154 (5), 1465-1479. e13, 2018 | 245 | 2018 |
| Removal of acetaminophen protein adducts by autophagy protects against acetaminophen-induced liver injury in mice HM Ni, MR McGill, X Chao, K Du, JA Williams, Y Xie, H Jaeschke, ... Journal of hepatology 65 (2), 354-362, 2016 | 199 | 2016 |
| Mitochondria-targeted antioxidant Mito-Tempo protects against acetaminophen hepatotoxicity K Du, A Farhood, H Jaeschke Archives of toxicology 91, 761-773, 2017 | 169 | 2017 |
| Critical role of FoxO3a in alcohol-induced autophagy and hepatotoxicity HM Ni, K Du, M You, WX Ding The American journal of pathology 183 (6), 1815-1825, 2013 | 163 | 2013 |
| Lower susceptibility of female mice to acetaminophen hepatotoxicity: Role of mitochondrial glutathione, oxidant stress and c-jun N-terminal kinase K Du, CD Williams, MR McGill, H Jaeschke Toxicology and applied pharmacology 281 (1), 58-66, 2014 | 111 | 2014 |
| Mitochondrial protein adducts formation and mitochondrial dysfunction during N-acetyl-m-aminophenol (AMAP)-induced hepatotoxicity in primary human hepatocytes Y Xie, MR McGill, K Du, K Dorko, SC Kumer, TM Schmitt, WX Ding, ... Toxicology and applied pharmacology 289 (2), 213-222, 2015 | 91 | 2015 |
| Induction of mitochondrial biogenesis protects against acetaminophen hepatotoxicity K Du, A Ramachandran, MR McGill, A Mansouri, T Asselah, A Farhood, ... Food and chemical toxicology 108, 339-350, 2017 | 79 | 2017 |
| Editor’s highlight: metformin protects against acetaminophen hepatotoxicity by attenuation of mitochondrial oxidant stress and dysfunction K Du, A Ramachandran, JL Weemhoff, H Chavan, Y Xie, P Krishnamurthy, ... Toxicological Sciences 154 (2), 214-226, 2016 | 70 | 2016 |
| Pathophysiological significance of c-jun N-terminal kinase in acetaminophen hepatotoxicity K Du, Y Xie, MR McGill, H Jaeschke Expert opinion on drug metabolism & toxicology 11 (11), 1769-1779, 2015 | 65 | 2015 |
| Increased glutaminolysis marks active scarring in nonalcoholic steatohepatitis progression K Du, SK Chitneni, A Suzuki, Y Wang, R Henao, J Hyun, RT Premont, ... Cellular and molecular gastroenterology and hepatology 10 (1), 1-21, 2020 | 64 | 2020 |
| Resveratrol prevents protein nitration and release of endonucleases from mitochondria during acetaminophen hepatotoxicity K Du, MR McGill, Y Xie, ML Bajt, H Jaeschke Food and Chemical Toxicology 81, 62-70, 2015 | 62 | 2015 |
| Dual role of epidermal growth factor receptor in liver injury and regeneration after acetaminophen overdose in mice B Bhushan, H Chavan, P Borude, Y Xie, K Du, MR McGill, M Lebofsky, ... Toxicological Sciences 155 (2), 363-378, 2017 | 56 | 2017 |
| Epithelial splicing regulatory protein 2–mediated alternative splicing reprograms hepatocytes in severe alcoholic hepatitis J Hyun, Z Sun, AR Ahmadi, S Bangru, UV Chembazhi, K Du, T Chen, ... The Journal of clinical investigation 130 (4), 2129-2145, 2020 | 53 | 2020 |
| Mito-tempo protects against acute liver injury but induces limited secondary apoptosis during the late phase of acetaminophen hepatotoxicity K Du, A Ramachandran, JL Weemhoff, BL Woolbright, AH Jaeschke, ... Archives of toxicology 93, 163-178, 2019 | 53 | 2019 |
| The gap junction inhibitor 2-aminoethoxy-diphenyl-borate protects against acetaminophen hepatotoxicity by inhibiting cytochrome P450 enzymes and c-jun N-terminal kinase activation K Du, CD Williams, MR McGill, Y Xie, A Farhood, M Vinken, H Jaeschke Toxicology and applied pharmacology 273 (3), 484-491, 2013 | 51 | 2013 |
| Mitochondrial protein adduct and superoxide generation are prerequisites for early activation of c-jun N-terminal kinase within the cytosol after an acetaminophen overdose in mice NT Nguyen, K Du, JY Akakpo, DS Umbaugh, H Jaeschke, ... Toxicology letters 338, 21-31, 2021 | 44 | 2021 |
| Succinate‐GPR‐91 receptor signalling is responsible for nonalcoholic steatohepatitis‐associated fibrosis: Effects of DHA supplementation XJ Liu, L Xie, K Du, C Liu, NP Zhang, CJ Gu, Y Wang, MF Abdelmalek, ... Liver International 40 (4), 830-843, 2020 | 41 | 2020 |
| Critical review of resveratrol in xenobiotic-induced hepatotoxicity MR McGill, K Du, JL Weemhoff, H Jaeschke Food and chemical toxicology 86, 309-318, 2015 | 37 | 2015 |
| Differential susceptibility to acetaminophen-induced liver injury in sub-strains of C57BL/6 mice: 6N versus 6J L Duan, JS Davis, BL Woolbright, K Du, M Cahkraborty, J Weemhoff, ... Food and chemical toxicology 98, 107-118, 2016 | 36 | 2016 |
Hartmut JaeschkeUniversity Distinguished Professor and Chair, University of Kansas Medical CenterVerified email at kumc.edu
