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Delilah Hendriks
Delilah Hendriks
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Characterization of primary human hepatocyte spheroids as a model system for drug-induced liver injury, liver function and disease
CC Bell, DFG Hendriks, SML Moro, E Ellis, J Walsh, A Renblom, ...
Scientific reports 6 (1), 25187, 2016
5562016
Novel 3D culture systems for studies of human liver function and assessments of the hepatotoxicity of drugs and drug candidates
VM Lauschke, DFG Hendriks, CC Bell, TB Andersson, ...
Chemical research in toxicology 29 (12), 1936-1955, 2016
2182016
Fast and efficient generation of knock-in human organoids using homology-independent CRISPR–Cas9 precision genome editing
B Artegiani, D Hendriks, J Beumer, R Kok, X Zheng, I Joore, ...
Nature cell biology 22 (3), 321-331, 2020
1462020
Hepatic 3D spheroid models for the detection and study of compounds with cholestatic liability
DFG Hendriks, L Fredriksson Puigvert, S Messner, W Mortiz, ...
Scientific reports 6 (1), 1-12, 2016
1342016
High-resolution mRNA and secretome atlas of human enteroendocrine cells
J Beumer, J Puschhof, J Bauzß-Martinez, A MartÝnez-Silgado, ...
Cell 181 (6), 1291-1306. e19, 2020
1032020
Massive rearrangements of cellular MicroRNA signatures are key drivers of hepatocyte dedifferentiation
VM Lauschke, SU Vorrink, SML Moro, F Rezayee, ┼ Nordling, ...
Hepatology 64 (5), 1743-1756, 2016
1022016
Building consensus on definition and nomenclature of hepatic, pancreatic, and biliary organoids
A Marsee, FJM Roos, MMA Verstegen, F Roos, M Verstegen, H Clevers, ...
Cell Stem Cell 28 (5), 816-832, 2021
972021
3D primary hepatocyte culture systems for analyses of liver diseases, drug metabolism, and toxicity: emerging culture paradigms and applications
VM Lauschke, RZ Shafagh, DFG Hendriks, M Ingelman‐Sundberg
Biotechnology journal 14 (7), 1800347, 2019
972019
Three-dimensional spheroid primary human hepatocytes in monoculture and coculture with nonparenchymal cells
A Baze, C Parmentier, DFG Hendriks, T Hurrell, B Heyd, P Bachellier, ...
Tissue Engineering Part C: Methods 24 (9), 534-545, 2018
762018
CRISPR-Cas tools and their application in genetic engineering of human stem cells and organoids
D Hendriks, H Clevers, B Artegiani
Cell Stem Cell 27 (5), 705-731, 2020
742020
Establishment of human fetal hepatocyte organoids and CRISPR–Cas9-based gene knockin and knockout in organoid cultures from human liver
D Hendriks, B Artegiani, H Hu, S Chuva de Sousa Lopes, H Clevers
Nature Protocols 16 (1), 182-217, 2021
482021
New approach methodologies (NAMs) for human-relevant biokinetics predictions: Meeting the paradigm shift in toxicology towards an animal-free chemical risk assessment
A Punt, H Bouwmeester, BJ Blaauboer, S Coecke, B Hakkert, ...
ALTEX: Alternatives to Animal Experimentation 37 (4), 607-622, 2020
452020
Human liver spheroids as a model to study aetiology and treatment of hepatic fibrosis
T Hurrell, V Kastrinou-Lampou, A Fardellas, DFG Hendriks, ┼ Nordling, ...
Cells 9 (4), 964, 2020
382020
Innovative organotypic in vitro models for safety assessment: aligning with regulatory requirements and understanding models of the heart, skin, and liver as paradigms
CS Pridgeon, C Schlott, MW Wong, MB Heringa, T Heckel, J Leedale, ...
Archives of toxicology 92, 557-569, 2018
382018
Human NAD (P) H: quinone oxidoreductase 1 (NQO1)-mediated inactivation of reactive quinoneimine metabolites of diclofenac and mefenamic acid
G Vredenburg, NS Elias, H Venkataraman, DFG Hendriks, ...
Chemical research in toxicology 27 (4), 576-586, 2014
362014
Expression and function of mARC: roles in lipogenesis and metabolic activation of ximelagatran
EPA Neve, H K÷feler, DFG Hendriks, ┼ Nordling, V Gogvadze, ...
PLoS One 10 (9), e0138487, 2015
292015
Clinically relevant cytochrome P450 3A4 induction mechanisms and drug screening in three‐dimensional spheroid cultures of primary human hepatocytes
DFG Hendriks, SU Vorrink, T Smutny, SC Sim, ┼ Nordling, S Ullah, ...
Clinical Pharmacology & Therapeutics 108 (4), 844-855, 2020
262020
Inter-individual differences in the susceptibility of primary human hepatocytes towards drug-induced cholestasis are compound and time dependent
C Parmentier, DFG Hendriks, B Heyd, P Bachellier, ...
Toxicology letters 295, 187-194, 2018
192018
Mechanisms of chronic fialuridine hepatotoxicity as revealed in primary human hepatocyte spheroids
DFG Hendriks, T Hurrell, J Riede, M van der Horst, S Tuovinen, ...
Toxicological Sciences 171 (2), 385-395, 2019
162019
In vitro grafting of hepatic spheroids and organoids on a microfluidic vascular bed
F Bonanini, D Kurek, S Previdi, A Nicolas, D Hendriks, S de Ruiter, ...
Angiogenesis 25 (4), 455-470, 2022
92022
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Artikelen 1–20