Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion F Rodier, JP Coppé, CK Patil, WAM Hoeijmakers, DP Muñoz, SR Raza, ... Nature cell biology 11 (8), 973-979, 2009 | 1590 | 2009 |
Inflammatory networks during cellular senescence: causes and consequences A Freund, AV Orjalo, PY Desprez, J Campisi Trends in molecular medicine 16 (5), 238-246, 2010 | 1018 | 2010 |
p38MAPK is a novel DNA damage response‐independent regulator of the senescence‐associated secretory phenotype A Freund, CK Patil, J Campisi The EMBO journal 30 (8), 1536-1548, 2011 | 615 | 2011 |
MTOR regulates the pro-tumorigenic senescence-associated secretory phenotype by promoting IL1A translation RM Laberge, YU Sun, AV Orjalo, CK Patil, A Freund, L Zhou, SC Curran, ... Nature cell biology 17 (8), 1049-1061, 2015 | 555 | 2015 |
Lamin B1 loss is a senescence-associated biomarker A Freund, RM Laberge, M Demaria, J Campisi Molecular biology of the cell 23 (11), 2066-2075, 2012 | 471 | 2012 |
Mitochondrial dysfunction induces senescence with a distinct secretory phenotype CD Wiley, MC Velarde, P Lecot, SU Liu, EA Sarnoski, A Freund, ... Cell metabolism 23 (2), 303-314, 2016 | 424 | 2016 |
Tumor suppressor and aging biomarker p16INK4a induces cellular senescence without the associated inflammatory secretory phenotype JP Coppé, F Rodier, CK Patil, A Freund, PY Desprez, J Campisi Journal of Biological Chemistry 286 (42), 36396-36403, 2011 | 324 | 2011 |
TPP1 OB-fold domain controls telomere maintenance by recruiting telomerase to chromosome ends FL Zhong, LFZ Batista, A Freund, MF Pech, AS Venteicher, SE Artandi Cell 150 (3), 481-494, 2012 | 260 | 2012 |
Dual SMAD signaling inhibition enables long-term expansion of diverse epithelial basal cells H Mou, V Vinarsky, PR Tata, K Brazauskas, SH Choi, AK Crooke, B Zhang, ... Cell stem cell 19 (2), 217-231, 2016 | 183 | 2016 |
Glucocorticoids suppress selected components of the senescence‐associated secretory phenotype RM Laberge, L Zhou, MR Sarantos, F Rodier, A Freund, PLJ de Keizer, ... Aging cell 11 (4), 569-578, 2012 | 140 | 2012 |
Proteostatic control of telomerase function through TRiC-mediated folding of TCAB1 A Freund, FL Zhong, AS Venteicher, Z Meng, TD Veenstra, J Frydman, ... Cell 159 (6), 1389-1403, 2014 | 83 | 2014 |
An activity switch in human telomerase based on RNA conformation and shaped by TCAB1 L Chen, CM Roake, A Freund, PJ Batista, S Tian, YA Yin, CR Gajera, ... Cell 174 (1), 218-230. e13, 2018 | 28 | 2018 |
Targetable mechanisms driving immunoevasion of persistent senescent cells link chemotherapy-resistant cancer to aging DP Muñoz, SM Yannone, A Daemen, Y Sun, F Vakar-Lopez, M Kawahara, ... JCI insight 4 (14), 2019 | 26 | 2019 |
Untangling aging using dynamic, organism-level phenotypic networks A Freund Cell systems 8 (3), 172-181, 2019 | 5 | 2019 |
Pharmacological inhibition of longevity regulator PAPP-A restrains mesenchymal stromal cell activity M Mohrin, J Liu, J Zavala-Solorio, S Bhargava, JM Trumble, A Brito, D Hu, ... bioRxiv, 2020 | 1 | 2020 |
Inhibition of longevity regulator PAPP‐A modulates tissue homeostasis via restraint of mesenchymal stromal cells M Mohrin, J Liu, J Zavala‐Solorio, S Bhargava, J Maxwell Trumble, A Brito, ... Aging Cell, e13313, 2021 | | 2021 |
ARDD 2020: from aging mechanisms to interventions GV Mkrtchyan, K Abdelmohsen, P Andreux, I Bagdonaite, N Barzilai, ... Aging (Albany NY) 12 (24), 24484, 2020 | | 2020 |
Age and diet shape the genetic architecture of body weight in Diversity Outbred mice KM Wright, A Deighan, A Di Francesco, A Freund, V Jojic, GA Churchill, ... bioRxiv, 2020 | | 2020 |
Signaling pathways that regulate cellular senescence AM Freund University of California, Berkeley, 2010 | | 2010 |