| In vivo transcriptional governance of hair follicle stem cells by canonical Wnt regulators WH Lien, L Polak, M Lin, K Lay, D Zheng, E Fuchs Nature cell biology 16 (2), 179, 2014 | 226 | 2014 |
| Enteroviral 3C protease activates the human NLRP1 inflammasome in airway epithelia KS Robinson, DET Teo, KS Tan, GA Toh, HH Ong, CK Lim, K Lay, BV Au, ... Science 370 (6521), 2020 | 187 | 2020 |
| Valproic acid confers functional pluripotency to human amniotic fluid stem cells in a transgene-free approach D Moschidou, S Mukherjee, MP Blundell, K Drews, GN Jones, ... Molecular Therapy 20 (10), 1953-1967, 2012 | 177 | 2012 |
| Modeling of lamin A/C mutation premature cardiac aging using patient-specific induced pluripotent stem cells CW Siu, YK Lee, JCY Ho, WH Lai, YC Chan, KM Ng, LY Wong, KW Au, ... Aging (Albany NY) 4 (11), 803, 2012 | 144 | 2012 |
| FOXC1 maintains the hair follicle stem cell niche and governs stem cell quiescence to preserve long-term tissue-regenerating potential K Lay, T Kume, E Fuchs Proceedings of the National Academy of Sciences 113 (11), E1506-E1515, 2016 | 142 | 2016 |
| Patient-specific induced-pluripotent stem cells-derived cardiomyocytes recapitulate the pathogenic phenotypes of dilated cardiomyopathy due to a novel DES mutation identified … HF Tse, JCY Ho, SW Choi, YK Lee, AW Butler, KM Ng, CW Siu, ... Human molecular genetics 22 (7), 1395-1403, 2013 | 119 | 2013 |
| NOVA-dependent regulation of cryptic NMD exons controls synaptic protein levels after seizure T Eom, C Zhang, H Wang, K Lay, J Fak, JL Noebels, RB Darnell Elife 2, e00178, 2013 | 117 | 2013 |
| Human NLRP1 is a sensor of pathogenic coronavirus 3CL proteases in lung epithelial cells R Planès, M Pinilla, K Santoni, A Hessel, C Passemar, K Lay, P Paillette, ... Molecular cell 82 (13), 2385-2400. e9, 2022 | 83 | 2022 |
| Upregulating CXCR4 in human fetal mesenchymal stem cells enhances engraftment and bone mechanics in a mouse model of osteogenesis imperfecta GN Jones, D Moschidou, K Lay, H Abdulrazzak, M Vanleene, ... Stem cells translational medicine 1 (1), 70-78, 2012 | 76 | 2012 |
| A comprehensive analysis of the effects of the deaminase AID on the transcriptome and methylome of activated B cells EL Fritz, BR Rosenberg, K Lay, A Mihailović, T Tuschl, FN Papavasiliou Nature immunology 14 (7), 749, 2013 | 74 | 2013 |
| Stem cells expand potency and alter tissue fitness by accumulating diverse epigenetic memories KAU Gonzales, L Polak, I Matos, MT Tierney, A Gola, E Wong, ... Science 374 (6571), eabh2444, 2021 | 70 | 2021 |
| Structural basis for distinct inflammasome complex assembly by human NLRP1 and CARD8 Q Gong, K Robinson, C Xu, PT Huynh, KHC Chong, EYJ Tan, J Zhang, ... Nature communications 12 (1), 1-15, 2021 | 64 | 2021 |
| Stem cells repurpose proliferation to contain a breach in their niche barrier K Lay, S Yuan, S Gur-Cohen, Y Miao, T Han, S Naik, HA Pasolli, ... eLife 7, e41661, 2018 | 44 | 2018 |
| Regulation of expression of the rat orthologue of mouse double minute 2 (MDM2) by H2O2-induced oxidative stress in neonatal rat cardiac myocytes S Pikkarainen, RA Kennedy, AK Marshall, K Lay, TA Kriz, BS Handa, ... Journal of Biological Chemistry, jbc. M109. 037887, 2009 | 31 | 2009 |
| The cardiomyocyte “redox rheostat”: redox signalling via the AMPK-mTOR axis and regulation of gene and protein expression balancing survival and death DN Meijles, G Zoumpoulidou, T Markou, KA Rostron, R Patel, K Lay, ... Journal of molecular and cellular cardiology 129, 118-129, 2019 | 28 | 2019 |
| DPP9 deficiency: An inflammasomopathy that can be rescued by lowering NLRP1/IL-1 signaling CR Harapas, KS Robinson, K Lay, J Wong, R Moreno Traspas, ... Science immunology 7 (75), eabi4611, 2022 | 24 | 2022 |
| Loss of FOCAD, operating via the SKI messenger RNA surveillance pathway, causes a pediatric syndrome with liver cirrhosis R Moreno Traspas, TS Teoh, PM Wong, M Maier, CY Chia, K Lay, NA Ali, ... Nature genetics 54 (8), 1214-1226, 2022 | 8 | 2022 |
| A homozygous p.Leu813Pro gain-of-function NLRP1 variant causes phenotypes of different severity in two siblings M Li, K Lay, A Zimmer, K Technau-Hafsi, J Wong, ... British Journal of Dermatology 188 (2), 259-267, 2023 | 6 | 2023 |
| Transcriptional Governance of Hair Follicle Stem Cell Quiescence and Niche Maintenance in Long-Term Tissue Regeneration K Lay | | 2017 |
| 013 Regulation of gene transcription by hydrogen peroxide in cardiomyocytes K Lay Heart 96 (4), e4-e4, 2010 | | 2010 |
