Jayesh A. Kulkarni
Jayesh A. Kulkarni
Nanomedicines Research Group
Geverifieerd e-mailadres voor alumni.ubc.ca - Homepage
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Lipid nanoparticles enabling gene therapies: from concepts to clinical utility
JA Kulkarni, PR Cullis, R Van Der Meel
Nucleic acid therapeutics 28 (3), 146-157, 2018
642018
On the formation and morphology of lipid nanoparticles containing ionizable cationic lipids and siRNA
JA Kulkarni, MM Darjuan, JE Mercer, S Chen, R Van Der Meel, ...
ACS nano 12 (5), 4787-4795, 2018
442018
The Onpattro story and the clinical translation of nanomedicines containing nucleic acid-based drugs
A Akinc, MA Maier, M Manoharan, K Fitzgerald, M Jayaraman, S Barros, ...
Nature Nanotechnology 14 (12), 1084-1087, 2019
432019
Design of lipid nanoparticles for in vitro and in vivo delivery of plasmid DNA
JA Kulkarni, JL Myhre, S Chen, YYC Tam, A Danescu, JM Richman, ...
Nanomedicine: Nanotechnology, Biology and Medicine 13 (4), 1377-1387, 2017
352017
Rapid synthesis of lipid nanoparticles containing hydrophobic inorganic nanoparticles
JA Kulkarni, YYC Tam, S Chen, YK Tam, J Zaifman, PR Cullis, S Biswas
Nanoscale 9 (36), 13600-13609, 2017
242017
Lipid nanoparticle technology for clinical translation of siRNA therapeutics
JA Kulkarni, D Witzigmann, S Chen, PR Cullis, R van der Meel
Accounts of chemical research 52 (9), 2435-2444, 2019
172019
State‐of‐the‐Art Design and Rapid‐Mixing Production Techniques of Lipid Nanoparticles for Nucleic Acid Delivery
MJW Evers, JA Kulkarni, R van der Meel, PR Cullis, P Vader, ...
Small Methods 2 (9), 1700375, 2018
172018
Systemic study of solvent-assisted active loading of gambogic acid into liposomes and its formulation optimization for improved delivery
WL Tang, WH Tang, A Szeitz, J Kulkarni, P Cullis, SD Li
Biomaterials 166, 13-26, 2018
172018
Dexamethasone prodrugs as potent suppressors of the immunostimulatory effects of lipid nanoparticle formulations of nucleic acids
S Chen, J Zaifman, JA Kulkarni, IV Zhigaltsev, YK Tam, MA Ciufolini, ...
Journal of controlled release 286, 46-54, 2018
112018
Fusion-dependent formation of lipid nanoparticles containing macromolecular payloads
JA Kulkarni, D Witzigmann, J Leung, R van der Meel, J Zaifman, ...
Nanoscale 11 (18), 9023-9031, 2019
92019
Characterization of a liposomal copper (II)-quercetin formulation suitable for parenteral use
KTJ Chen, M Anantha, AWY Leung, JA Kulkarni, GGC Militao, M Wehbe, ...
Drug delivery and translational research 10 (1), 202-215, 2020
62020
Coating of PLA-nanoparticles with cyclic, arginine-rich cell penetrating peptides enables oral delivery of liraglutide
P Uhl, C Grundmann, M Sauter, P Storck, A Tursch, S Özbek, K Leotta, ...
Nanomedicine: Nanotechnology, Biology and Medicine 24, 102132, 2020
52020
On the role of helper lipids in lipid nanoparticle formulations of siRNA
JA Kulkarni, D Witzigmann, J Leung, YYC Tam, PR Cullis
Nanoscale 11 (45), 21733-21739, 2019
52019
Use of a lipid nanoparticle system as a Trojan horse in delivery of gold nanoparticles to human breast cancer cells for improved outcomes in radiation therapy
K Bromma, K Rieck, J Kulkarni, C O’Sullivan, W Sung, P Cullis, ...
Cancer Nanotechnology 10 (1), 1-17, 2019
32019
Robust Microfluidic Technology and New Lipid Composition for Fabrication of Curcumin-Loaded Liposomes: Effect on the Anticancer Activity and Safety of Cisplatin
N Hamano, R Böttger, SE Lee, Y Yang, JA Kulkarni, S Ip, PR Cullis, ...
Molecular pharmaceutics 16 (9), 3957-3967, 2019
32019
Ionizable amino lipid interactions with POPC: implications for lipid nanoparticle function
M Ramezanpour, ML Schmidt, I Bodnariuc, JA Kulkarni, SSW Leung, ...
Nanoscale 11 (30), 14141-14146, 2019
32019
Phospholipid‐Free Small Unilamellar Vesicles for Drug Targeting to Cells in the Liver
W Zhang, R Böttger, Z Qin, JA Kulkarni, J Vogler, PR Cullis, SD Li
Small 15 (43), 1901782, 2019
22019
Next generation magnetic lipid nanohybrids for theranostics
S Biswas, J Kulkarni, Y Tam, Y Tam, P Cullis
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 250, 2015
12015
Sustained Depletion of FXIII-A by Inducing Acquired FXIII-B Deficiency
AW Strilchuk, SC Meixner, J Leung, N Safikhan, JA Kulkarni, HM Russell, ...
Blood, 2020
2020
Lipid nanoparticle technology for therapeutic gene regulation in the liver
D Witzigmann, JA Kulkarni, J Leung, S Chen, PR Cullis, R van der Meel
Advanced Drug Delivery Reviews, 2020
2020
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