The interaction of blood platelets with collagen is generally considered to be of primary
importance in the arrest of bleeding and to have a role in the pathogenesis of thrombosis and …

… and Akkerman JWN (1999) Low-density lipoprotein enhances platelet secretion via
integrin-aIIbb3… and Akkerman JWN (1992) Arachidonate transfer between platelets and …

There is a strong correlation between the level of plasma low-density lipoprotein (LDL) and
death by cardiovascular disease (CVD). As a main carrier of cholesterol, a high low-density …

Platelets are the second most abundant cell type in blood and are essential for maintaining
haemostasis. Their count and volume are tightly controlled within narrow physiological …

Rap1 is a small, Ras‐like GTPase whose function and regulation are still largely unknown.
We have developed a novel assay to monitor the active, GTP‐bound form of Rap1 based on …

Metabolic studies have revealed a gradual impairment in platelet integrity during storage, a
process termed the platelet storage lesion. Recent evidence shows that stored platelets also …

Objective— ADP-induced P2y 12 signaling is crucial for formation and stabilization of an
arterial thrombus. We demonstrated recently in platelets from healthy subjects that insulin …

OBJECTIVE To assess the effects of low-dose eicosapentaenoic acid-ethyl-ester on diabetes
regulation, lipid metabolism, blood rheology, and platelet reactivity. RESEARCH DESIGN …

Platelet aggregation is initiated by the release of mediators as adenosine diphosphate (ADP)
stored in platelet granules. Possible candidates for transport proteins mediating …

Compared with conventional transfusion regimes a strong reduction in HLA alloimmunization
and refractoriness to platelet transfusions is obtained when both red blood cell …