The purpose of this review is to summarize emerging evidence that the neurobehavioral
features of Lesch–Nyhan disease (LND), a developmental disorder caused by congenital …

The endocannabinoid system is a valuable target for drug discovery, because it is involved
in the regulation of many cellular and physiological functions. The endocannabinoid system …

Apo-ptosis, derived from Greek for 'falling off, can refer to the falling off of leaves during autumn
(1), but is currently often used to describe a particular cell behaviour which occurs during …

The absorption spectrum of human fibroblast monolayers showed several absorption peaks,
among them one at a wavelength of 630 nm. Cultures of these fibroblasts were subjected to …

Transgenic mice that overexpress the mutant human SOD1 gene (hSOD1) serve as an animal
model for amyotrophic lateral sclerosis (ALS). Age and sex are recognized as risk factors …

The effect of a combination of a warm-up, stretching exercises and massage on subjective
scores for delayed onset muscle soreness (DOMS) and objective functional and biochemical …

During development, neurotrophic factors play an important role in the guidance and
outgrowth of axons. Our working hypothesis is that neurotrophic factors involved in the …

Excitotoxicity is a paradigm used to explain the biochemical events in both acute neuronal
damage and in slowly progressive, neurodegenerative diseases. Here, we show in a …

Neuromuscular synapses differ markedly in their plasticity. Motor nerve terminals innervating
slow muscle fibers sprout vigorously following synaptic blockage, while those innervating …

The endocannabinoid anandamide [N-arachidonoylethanolamine (AEA)] is thought to function
as an endogenous protective factor of the brain against acute neuronal damage. However…