The hallmarks of CMV-specific CD8 T-cell differentiation
SPH van den Berg, IN Pardieck, J Lanfermeijer… - Medical microbiology …, 2019 - Springer
Upon cytomegalovirus (CMV) infection, large T-cell responses are elicited that remain high
or even increase over time, a phenomenon named memory T-cell inflation. Besides, the …
or even increase over time, a phenomenon named memory T-cell inflation. Besides, the …
Effect of latent cytomegalovirus infection on the antibody response to influenza vaccination: a systematic review and meta-analysis
SPH Van den Berg, K Warmink, JAM Borghans… - Medical microbiology …, 2019 - Springer
Latent infection with cytomegalovirus (CMV) is thought to accelerate aging of the immune
system. With age, influenza vaccine responses are impaired. Although several studies …
system. With age, influenza vaccine responses are impaired. Although several studies …
Mode of delivery modulates the intestinal microbiota and impacts the response to vaccination
EM de Koff, D van Baarle, MA van Houten… - Nature …, 2022 - nature.com
The gut microbiota in early life, when critical immune maturation takes place, may influence
the immunogenicity of childhood vaccinations. Here we assess the association between …
the immunogenicity of childhood vaccinations. Here we assess the association between …
Objectively measured physical activity of hospital shift workers
B Loef, AJ Van Der Beek, A Holtermann… - Scandinavian journal of …, 2018 - JSTOR
Objectives Shift work may alter workers' leisure-time and occupational physical activity (PA)
levels, which might be one of the potential underlying mechanisms of the negative health …
levels, which might be one of the potential underlying mechanisms of the negative health …
Night-shift work is associated with increased susceptibility to SARS-CoV-2 infection
B Loef, MET Dollé, KI Proper, D van Baarle… - Chronobiology …, 2022 - Taylor & Francis
Night-shift workers experience disturbances of their circadian rhythm and sleep, which may
make them more susceptible to infectious diseases. Therefore, we studied whether night-…
make them more susceptible to infectious diseases. Therefore, we studied whether night-…
Age and CMV-Infection Jointly Affect the EBV-Specific CD8+ T-Cell Repertoire
J Lanfermeijer, PC de Greef, M Hendriks, M Vos… - Frontiers in …, 2021 - frontiersin.org
CD8 + T cells play an important role in protection against viral infections. With age, changes
in the T-cell pool occur, leading to diminished responses against both new and recurring …
in the T-cell pool occur, leading to diminished responses against both new and recurring …
Klokwerk+ study protocol: An observational study to the effects of night–shift work on body weight and infection susceptibility and the mechanisms underlying these …
B Loef, D van Baarle, AJ van der Beek… - BMC public health, 2016 - Springer
Klokwerk + study protocol: An observational study to the effects of night–shift work on body
weight and infection susceptibility and the mechanisms underlying these health effects | BMC …
weight and infection susceptibility and the mechanisms underlying these health effects | BMC …
On the feasibility of using TCR sequencing to follow a vaccination response–lessons learned
PC de Greef, J Lanfermeijer, M Hendriks… - Frontiers in …, 2023 - frontiersin.org
T cells recognize pathogens by their highly specific T-cell receptor (TCR), which can bind
small fragments of an antigen presented on the Major Histocompatibility Complex (MHC). …
small fragments of an antigen presented on the Major Histocompatibility Complex (MHC). …
Co-Expression of TIGIT and Helios Marks Immunosenescent CD8+ T Cells During Aging
DKJ Pieren, NAM Smits, RJ Postel, V Kandiah… - Frontiers in …, 2022 - frontiersin.org
Aging leads to alterations in the immune system that result in ineffective responsiveness
against pathogens. Features of this process, collectively known as immunosenescence, …
against pathogens. Features of this process, collectively known as immunosenescence, …
Ferric carboxymaltose and SARS-CoV-2 vaccination-induced immunogenicity in kidney transplant recipients with iron deficiency: The COVAC-EFFECT randomized …
JSJ Vinke, DHA Altulea, MF Eisenga… - Frontiers in …, 2023 - frontiersin.org
Background Kidney transplant recipients (KTRs) have an impaired immune response after
vaccination against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Iron …
vaccination against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Iron …