The aim of the current study was twofold: (1) to systematically examine differences in fear
conditioning between anxiety patients and healthy controls using meta‐analytic methods, and (…

The so-called ‘replicability crisis’ has sparked methodological discussions in many areas of
science in general, and in psychology in particular. This has led to recent endeavours to …

The endocannabinoid system is a promising candidate for anxiolytic therapy, but translation
to the clinic has been lagging. We meta-analyzed the evidence for anxiety-reduction by …

BACKGROUND: Sustained anxiety can be modeled using context conditioning, which can
be studied in a virtual reality environment. Unpredictable stressors increase context …

BACKGROUND: The startle reflex is potentiated by aversive states. It has been proposed
that phasic startle potentiation to a threat cue and sustained startle potentiation to contextual …

The Stimulus-Preceding Negativity (SPN), a slow cortical potential, has been studied in
relation to anticipatory attention. A review of the literature suggests that most instances of SPN …

Stimulus novelty or deviance may be especially salient in anxiety-related states due to
sensitization to environmental change, a key symptom of anxiety disorders such as posttraumatic …

The acquisition of a conditioned fear response is adaptive, as it enables the organism to
appropriately respond to predictors of aversive events. Consequently, the absence of predictive …

The ability to adaptively regulate responses to the proximity of potential danger is critical to
survival and imbalance in this system may contribute to psychopathology. The bed nucleus of …

Recent cross-sectional studies have shown that the inability to suppress fear under safe
conditions is a key problem in people with posttraumatic stress disorder (PTSD). The current …