Importance Reliable prevalence estimates are lacking for young-onset dementia (YOD), in
which symptoms of dementia start before the age of 65 years. Such estimates are needed for …

PURPOSE: To determine the normal values and effects of age and sex on total cerebral
blood flow (CBF) as measured with ungated two-dimensional phase-contrast magnetic …

Objective When it comes to dementia, caregiving can have adverse effects on the psychological
and physical health of the informal caregiver. As yet, little is known about the impact of …

CD28 and CTLA-4 are related glycoproteins found on T cells. Ligation of CD28 following
antigen receptor engagement provides a costimulatory signal required for T cell activation. Anti-…

The human Dubin-Johnson syndrome and its animal model, the TR − rat, are characterized
by a chronic conjugated hyperbilirubinemia. TR − rats are defective in the canalicular …

Male patients with fragile X syndrome lack FMR1 protein due to silencing of the FMR1 gene
by amplification of a CGG repeat and subsequent methylation of the promoter region. The …

We developed a method for calculating adipose-tissue areas from transverse body scans by
magnetic-resonance imaging (MRI). The method is based on an inversion recovery …

In a circular economy (CE), the economic and environmental value of materials is preserved
for as long as possible by keeping them in the economic system, either by lengthening the …

Absence of functional FMRP causes Fragile X syndrome. Abnormalities in synaptic processes
in the cerebral cortex and hippocampus contribute to cognitive deficits in Fragile X patients…

Objective The quality of colonoscopy is key for ensuring protection against colorectal cancer
(CRC). We therefore aimed to elucidate the aetiology of postcolonoscopy CRCs (PCCRCs), …