Gebruikersprofielen voor "Baldus, M. "

Marc Baldus

Utrecht University, Bijvoet Center for Biomolecular Research
Geverifieerd e-mailadres voor uu.nl
Geciteerd door 18418

Correlation experiments for assignment and structure elucidation of immobilized polypeptides under magic angle spinning

M Baldus - Progress in Nuclear Magnetic Resonance …, 2002 - Elsevier
Correlation experiments for assignment and structure elucidation of immobilized polypeptides
under magic angle spinning - ScienceDirect Skip to main contentSkip to article Elsevier …

Solid‐state NMR spectroscopy on complex biomolecules

M Renault, A Cukkemane… - Angewandte Chemie …, 2010 - Wiley Online Library
Biomolecular applications of NMR spectroscopy are often merely associated with soluble
molecules or magnetic resonance imaging. However, since the late 1970s, solid‐state NMR (…

Cross polarization in the tilted frame: assignment and spectral simplification in heteronuclear spin systems

M Baldus, AT Petkova, J Herzfeld, RG Griffin - Molecular Physics, 1998 - Taylor & Francis
A frequency selective heteronuclear polarization transfer technique is introduced for rotating
solids. In this method, radiofrequency fields comparable with the frequency offsets are …

Solid-state NMR-based approaches for supramolecular structure elucidation

M Weingarth, M Baldus - Accounts of chemical research, 2013 - ACS Publications
Supramolecular chemistry provides structural and conformational information about
complexes formed from multiple molecules. While the molecule is held together by strong …

Toxin-induced conformational changes in a potassium channel revealed by solid-state NMR

A Lange, K Giller, S Hornig, MF Martin-Eauclaire… - Nature, 2006 - nature.com
The active site of potassium (K + ) channels catalyses the transport of K + ions across the
plasma membrane 1 —similar to the catalytic function of the active site of an enzyme—and is …

Molecular-level secondary structure, polymorphism, and dynamics of full-length α-synuclein fibrils studied by solid-state NMR

H Heise, W Hoyer, S Becker… - Proceedings of the …, 2005 - National Acad Sciences
The 140-residue protein α-synuclein (AS) is able to form amyloid fibrils and as such is the
main component of protein inclusions involved in Parkinson's disease. We have investigated …

Cellular solid-state nuclear magnetic resonance spectroscopy

M Renault, R Tommassen-van Boxtel… - Proceedings of the …, 2012 - National Acad Sciences
Decrypting the structure, function, and molecular interactions of complex molecular machines
in their cellular context and at atomic resolution is of prime importance for understanding …

Pre‐fibrillar α‐synuclein variants with impaired β‐structure increase neurotoxicity in Parkinson's disease models

DP Karpinar, MBG Balija, S Kügler, F Opazo… - The EMBO …, 2009 - embopress.org
The relation of α‐synuclein (αS) aggregation to Parkinson's disease (PD) has long been
recognized, but the mechanism of toxicity, the pathogenic species and its molecular properties …

The conformation of neurotensin bound to its G protein-coupled receptor

S Luca, JF White, AK Sohal… - Proceedings of the …, 2003 - National Acad Sciences
G protein-coupled receptors (GPCRs) mediate the perception of smell, light, taste, and pain.
They are involved in signal recognition and cell communication and are some of the most …

EGFR dynamics change during activation in native membranes as revealed by NMR

M Kaplan, S Narasimhan, C De Heus, D Mance… - Cell, 2016 - cell.com
The epidermal growth factor receptor (EGFR) represents one of the most common target
proteins in anti-cancer therapy. To directly examine the structural and dynamical properties of …