Gebruikersprofielen voor "Baubec, T. "
![]() | Tuncay BaubecChair of Genome Biology & Epigenetics, Utrecht University Geverifieerd e-mailadres voor uu.nl Geciteerd door 3580 |
Dynamics and context-dependent roles of DNA methylation
C Ambrosi, M Manzo, T Baubec - Journal of molecular biology, 2017 - Elsevier
DNA methylation is one of the most extensively studied epigenetic marks. It is involved in
transcriptional gene silencing and plays important roles during mammalian development. Its …
transcriptional gene silencing and plays important roles during mammalian development. Its …
Genomic patterns and context specific interpretation of DNA methylation
T Baubec, D Schübeler - Current opinion in genetics & development, 2014 - Elsevier
Methylation of CpG dinucleotides is a reversible modification of DNA that is highly prevalent
throughout mammalian genomes. Recent advances generated genomic DNA methylation …
throughout mammalian genomes. Recent advances generated genomic DNA methylation …
The Air noncoding RNA: an imprinted cis-silencing transcript
The observation that imprinted genes exist in clusters suggests that mechanisms to control
imprinted expression act on the chromosomal domain rather than on individual genes (Reik …
imprinted expression act on the chromosomal domain rather than on individual genes (Reik …
Genomic profiling of DNA methyltransferases reveals a role for DNMT3B in genic methylation
T Baubec, DF Colombo, C Wirbelauer, J Schmidt… - Nature, 2015 - nature.com
DNA methylation is an epigenetic modification associated with transcriptional repression of
promoters and is essential for mammalian development. Establishment of DNA methylation …
promoters and is essential for mammalian development. Establishment of DNA methylation …
Epigenetic Regulation of Repetitive Elements Is Attenuated by Prolonged Heat Stress in Arabidopsis
Epigenetic factors determine responses to internal and external stimuli in eukaryotic organisms.
Whether and how environmental conditions feed back to the epigenetic landscape is …
Whether and how environmental conditions feed back to the epigenetic landscape is …
[HTML][HTML] Methylation-dependent and-independent genomic targeting principles of the MBD protein family
To gain insight into the cellular readout of DNA methylation, we established a strategy for
systematically profiling the genome-wide distribution of chromatin-interacting factors. This …
systematically profiling the genome-wide distribution of chromatin-interacting factors. This …
Genome-scale CRISPR screening in human intestinal organoids identifies drivers of TGF-β resistance
T Ringel, N Frey, F Ringnalda, S Janjuha, S Cherkaoui… - Cell stem cell, 2020 - cell.com
Forward genetic screens with genome-wide CRISPR libraries are powerful tools for resolving
cellular circuits and signaling pathways. Applying this technology to organoids, however, …
cellular circuits and signaling pathways. Applying this technology to organoids, however, …
Dynamic and flexible H3K9me3 bridging via HP1β dimerization establishes a plastic state of condensed chromatin
K Hiragami-Hamada, S Soeroes, M Nikolov… - Nature …, 2016 - nature.com
Histone H3 trimethylation of lysine 9 (H3K9me3) and proteins of the heterochromatin protein
1 (HP1) family are hallmarks of heterochromatin, a state of compacted DNA essential for …
1 (HP1) family are hallmarks of heterochromatin, a state of compacted DNA essential for …
Genomic prevalence of heterochromatic H3K9me2 and transcription do not discriminate pluripotent from terminally differentiated cells
Cellular differentiation entails reprogramming of the transcriptome from a pluripotent to a
unipotent fate. This process was suggested to coincide with a global increase of repressive …
unipotent fate. This process was suggested to coincide with a global increase of repressive …
Effective, homogeneous and transient interference with cytosine methylation in plant genomic DNA by zebularine
Covalent modification by methylation of cytosine residues represents an important epigenetic
hallmark. While sequence analysis after bisulphite conversion allows correlative analyses …
hallmark. While sequence analysis after bisulphite conversion allows correlative analyses …