Gebruikersprofielen voor "Boeke, J. "
 | Jef D. BoekeNYU Langone Health Geverifieerd e-mailadres voor nyulangone.org Geciteerd door 72710 |
Transposable elements and genome organization: a comprehensive survey of retrotransposons revealed by the complete Saccharomyces cerevisiae genome …
We conducted a genome-wide survey of Saccharomyces cerevisiae retrotransposons and
identified a total of 331 insertions, including 217 Ty1, 34 Ty2, 41 Ty3, 32 Ty4, and 7 Ty5 …
identified a total of 331 insertions, including 217 Ty1, 34 Ty2, 41 Ty3, 32 Ty4, and 7 Ty5 …
Retrotransposons, endogenous retroviruses, and the evolution of retroelements
The retroelements are as diverse an assemblage of related molecular entities as can be
found anywhere. With the exception of the retroviruses themselves, retroelements are genetic …
found anywhere. With the exception of the retroviruses themselves, retroelements are genetic …
The role of retrotransposable elements in ageing and age-associated diseases
The genomes of virtually all organisms contain repetitive sequences that are generated by
the activity of transposable elements (transposons). Transposons are mobile genetic …
the activity of transposable elements (transposons). Transposons are mobile genetic …
Functional profiling of the Saccharomyces cerevisiae genome
Determining the effect of gene deletion is a fundamental approach to understanding gene
function. Conventional genetic screens exhibit biases, and genes contributing to a phenotype …
function. Conventional genetic screens exhibit biases, and genes contributing to a phenotype …
Functional Characterization of the S. cerevisiae Genome by Gene Deletion and Parallel Analysis
EA Winzeler, DD Shoemaker, A Astromoff, H Liang… - science, 1999 - science.org
The functions of many open reading frames (ORFs) identified in genome-sequencing projects
are unknown. New, whole-genome approaches are required to systematically determine …
are unknown. New, whole-genome approaches are required to systematically determine …
A phylogenetically conserved NAD+-dependent protein deacetylase activity in the Sir2 protein family
JS Smith, CB Brachmann, I Celic… - Proceedings of the …, 2000 - National Acad Sciences
The yeast Sir2 protein, required for transcriptional silencing, has an NAD + -dependent histone
deacetylase (HDA) activity. Yeast extracts contain a NAD + -dependent HDA activity that …
deacetylase (HDA) activity. Yeast extracts contain a NAD + -dependent HDA activity that …
Designer deletion strains derived from Saccharomyces cerevisiae S288C: A useful set of strains and plasmids for PCR‐mediated gene disruption and other …
C Baker Brachmann, A Davies, GJ Cost, E Caputo, J Li… - Yeast, 1998 - Wiley Online Library
A set of yeast strains based on Saccharomyces cerevisiae S288C in which commonly used
selectable marker genes are deleted by design based on the yeast genome sequence has …
selectable marker genes are deleted by design based on the yeast genome sequence has …
Sir2-dependent activation of acetyl-CoA synthetase by deacetylation of active lysine
Acetyl-coenzyme A (CoA) synthetase (Acs) is an enzyme central to metabolism in prokaryotes
and eukaryotes. Acs synthesizes acetyl CoA from acetate, adenosine triphosphate, and …
and eukaryotes. Acs synthesizes acetyl CoA from acetate, adenosine triphosphate, and …
Total synthesis of a functional designer eukaryotic chromosome
Rapid advances in DNA synthesis techniques have made it possible to engineer viruses,
biochemical pathways and assemble bacterial genomes. Here, we report the synthesis of a …
biochemical pathways and assemble bacterial genomes. Here, we report the synthesis of a …
Synthetic chromosome arms function in yeast and generate phenotypic diversity by design
JS Dymond, SM Richardson, CE Coombes, T Babatz… - Nature, 2011 - nature.com
Recent advances in DNA synthesis technology have enabled the construction of novel
genetic pathways and genomic elements, furthering our understanding of system-level …
genetic pathways and genomic elements, furthering our understanding of system-level …