Abstract S1-03: First results from the multicenter phase III DATA study comparing 3 versus 6 years of anastrozole after 2-3 years of tamoxifen in postmenopausal …
VC Tjan-Heijnen, IE Van Hellemond, PG Peer… - Cancer Research, 2017 - AACR
Background. Even in view of the recent findings of the MA.17R trial, the impact of prolonged
aromatase inhibitor (AI) therapy after prior tamoxifen in hormone receptor-positive early …
aromatase inhibitor (AI) therapy after prior tamoxifen in hormone receptor-positive early …
[PDF][PDF] Mutations in the X-linked and autosomal recessive forms of chronic granulomatous disease
D Roos, M de Boer, F Kuribayashi, C Meischl… - 1996 - researchgate.net
HRONIC granulomatous disease (CGD) is an immuno-C deficiency syndrome characterized
clinically by severe recurrent bacterial and fungal infections that are difficult to treat by …
clinically by severe recurrent bacterial and fungal infections that are difficult to treat by …
[PDF][PDF] CD80, CD86 and CD40 provide accessory signals in a multiple-step T-cell activation model
S Van Gool, P Vandenberghe, M de Boer… - Immunological …, 1997 - lirias.kuleuven.be
In this review, a sequential multiple-step model for T-cell activation is proposed. In a series of
in vitro studies, highly purified freshly isolated human peripheral blood T lymphocytes were …
in vitro studies, highly purified freshly isolated human peripheral blood T lymphocytes were …
Differential expression of SOX17 and SOX2 in germ cells and stem cells has biological and clinical implications
J de Jong, H Stoop, AJM Gillis… - The Journal of …, 2008 - Wiley Online Library
Combined action of SOX and POU families of transcription factors plays major roles in
embryonic development. In embryonic stem cells, the combination of SOX2 and POU5F1 (OCT3/4…
embryonic development. In embryonic stem cells, the combination of SOX2 and POU5F1 (OCT3/4…
Interleukin‐10 inhibits B7 and intercellular adhesion molecule‐1 expression on human monocytes
F Willems, A Marchant, JP Delville… - European journal of …, 1994 - Wiley Online Library
There is evidence that interleukin −10(IL‐10) interferes with the costimulatory properties of
antigen‐presenting cells and, thereby, inhibits their ability to induce T cell activation. To …
antigen‐presenting cells and, thereby, inhibits their ability to induce T cell activation. To …
A new exon created by intronic insertion of a rearranged LINE-1 element as the cause of chronic granulomatous disease
C Meischl, M de Boer, A Åhlin, D Roos - European Journal of Human …, 2000 - nature.com
Long interspersed nuclear element-1 (LINE-1) or L1 elements are DNA elements present in
the genome in high copy number and capable of active retrotransposition. Here we present …
the genome in high copy number and capable of active retrotransposition. Here we present …
Prevalence, genetics and clinical presentation of chronic granulomatous disease in Sweden
To estimate the prevalence of chronic granulomatous disease (CGD) in Sweden, an inquiry
asking for known and possible CGD cases was mailed to paediatric, internal medicine and …
asking for known and possible CGD cases was mailed to paediatric, internal medicine and …
Ligation of B7 with CD28/CTLA‐4 on T cells results in CD40 ligand expression, interleukin‐4 secretion and efficient help for antibody production by B cells
M de Boer, A Kasran, J Kwekkeboom… - European journal of …, 1993 - Wiley Online Library
It has been extensively shown that when T cells are co‐stimulated with B7‐CD28 interaction,
a strong proliferative as well as cytolytic T cell response can be induced. In contrast, there …
a strong proliferative as well as cytolytic T cell response can be induced. In contrast, there …
Increased cytolytic T lymphocyte activity and decreased B7 responsiveness are associated with CD28 down‐regulation on CD8+ T cells from HIV‐infected subjects
JH Vingerhoets, GL Vanham… - Clinical & …, 1995 - Wiley Online Library
The CD28 receptor on CD4 + and CD8 + T cells interacts with B7 molecules on antigen‐presenting
cells (APC) to generate essential costimulatory signals. The cytolytic potential of CD8 …
cells (APC) to generate essential costimulatory signals. The cytolytic potential of CD8 …
The B7/BB1 antigen is expressed by Reed-Sternberg cells of Hodgkin's disease and contributes to the stimulating capacity of Hodgkin's disease-derived cell lines
J Delabie, JL Ceuppens, P Vandenberghe, M de Boer… - 1993 - ashpublications.org
The B7/BB1 molecule has recently been found to be expressed on professional antigen-presenting
cells and to be the natural ligand for CD28 and CTLA-4 on T cells. On binding of B7/…
cells and to be the natural ligand for CD28 and CTLA-4 on T cells. On binding of B7/…