Synthesis of LD-Hepp and KDO containing di-and tetrasaccharide derivatives of Neisseria meningitidis inner-core region via iodonium ion promoted glycosidations

G Boons, FL Van Delft, PAM Van der Klein… - Tetrahedron, 1992 - Elsevier
The synthesis of methyl(ethyl) 2-thio-KDO ie1, 2, 5, 7 and 10 and ethyl 1-thio-ldHepp (ie26
and 43 derivatives will be described. The latter derivatives proved to be suitable donors in …

Identification of a secondary binding site in human macrophage galactose-type lectin by microarray studies: Implications for the molecular recognition of its ligands

F Marcelo, N Supekar, F Corzana… - Journal of Biological …, 2019 - ASBMB
The human macrophage galactose-type lectin (MGL) is a C-type lectin characterized by a
unique specificity for terminal GalNAc residues present in the tumor-associated Tn antigen (…

Hierarchical multivalent effects control influenza host specificity

NJ Overeem, PHE Hamming, OC Grant… - ACS central …, 2020 - ACS Publications
Understanding how emerging influenza viruses recognize host cells is critical in evaluating
their zoonotic potential, pathogenicity, and transmissibility between humans. The surface of …

Hydrolytic (in) stability of methacrylate esters in covalently cross-linked hydrogels based on chondroitin sulfate and hyaluronic acid methacrylate

CCL Schuurmans, AJ Brouwer, JAW Jong… - ACS …, 2021 - ACS Publications
Chondroitin sulfate (CS) and hyaluronic acid (HA) methacrylate (MA) hydrogels are under
investigation for biomedical applications. Here, the hydrolytic (in)stability of the MA esters in …

Glycoproteomics-compatible MS/MS-based quantification of glycopeptide isomers

JCL Maliepaard, JMA Damen, GJPH Boons… - Analytical …, 2023 - ACS Publications
Glycosylation is an essential protein modification occurring on the majority of extracellular
human proteins, with mass spectrometry (MS) being an indispensable tool for its analysis, that …

An efficient route to 3-deoxy-D-manno-2-octulosonic acid (KDO) derivatives via a 1, 4-cyclic sulfate approach

PAM Van der Klein, G Boons, GH Veeneman… - Tetrahedron letters, 1989 - Elsevier
Abstract Treatment of 2,3:5,6-di-O-isopropylidene-D-mannitol with thionyl chloride followed
by oxidation gave the corresponding 1,4-cyclic sulfate. Ring opening of the cyclic sulfate with …

A versatile and new highly stereoselective approach to the synthesis of L-glycero-D-manno-heptopyranosides

G Boons, GA Van der Marel, JH Van Boom - Tetrahedron letters, 1989 - Elsevier
The reaction of (phenyldimethyl)silylmethylmagnesium chloride with benzyl 2,3,4-tri-O-benzyl-α-D-manno-hexodialdo-1,5-pyranoside
affords the corresponding L-glycero-D-manno-…

Application of the Dimethyl(phenyl)silyl Group as a Masked Form of the Hydroxy Group in the Synthesis of an Lglycero‐α‐Dmanno‐heptopyranoside‐Containing …

G Boons, M Overhand… - … Edition in English, 1989 - Wiley Online Library
J,, 2= 3.0), 1.36 (7a-H and 7b-H) I. For the deblocking of 14 the base labile groups are cleaved
with NaOH. Subsequent reduction of the azido group with H2S* 161 is then followed by …

Use of (phenyldimethylsilyl) methoxymethyl and (phenyldimethylsilyl) methyl ethers as protecting groups for sugar hydroxyls

G Boons, CJJ Elie, GA van der Matel, JH van Boom - Tetrahedron letters, 1990 - Elsevier
The reagent (phenyldimethylsilyl)methoxymethyl chioride (SMOM-Cl) proved to be very
convenient for the formation of the corresponding SMOM ethers of primary and secondary …

Synthesis of L‐glycero‐D‐manno‐heptose

G Boons, PAM Van der Klein… - Recueil des Travaux …, 1988 - Wiley Online Library
Synthesis of Lâ•’<i>glycero</i>â•’Dâ•’<i>manno</i>â•’heptose Page 1 Recueil des Travaux
Chimiques des Pays-Bas, 10717-8, JulylAugust 1988 Recl. Trav. Chim. Pays-Bas 107, 507-508 …