Monocyte-chemoattractant protein-1 levels in human atherosclerotic lesions associate with plaque vulnerability

MK Georgakis, SW Van Der Laan, Y Asare… - … , and vascular biology, 2021 - ahajournals.org
Objective: To determine whether MCP-1 (monocyte chemoattractant protein 1) levels in
human atherosclerotic plaques associate with plaque vulnerability features. Approach and …

Atherosclerotic plaque epigenetic age acceleration predicts a poor prognosis and is associated with endothelial-to-mesenchymal transition in humans

E Diez Benavente, RJG Hartman… - … and Vascular Biology, 2024 - ahajournals.org
BACKGROUND: Epigenetic age estimators (clocks) are predictive of human mortality risk.
However, it is not yet known whether the epigenetic age of atherosclerotic plaques is …

Growth differentiation factor 15 is associated with major amputation and mortality in patients with peripheral artery disease

JJ De Haan, S Haitjema, HM den Ruijter… - Journal of the …, 2017 - ahajournals.org
Background Peripheral artery disease ( PAD ) is one of the most common clinical presentations
of atherosclerosis, and its prevalence is still increasing. Despite improvement of health …

Temporal trends and determinants of stroke risk in patients with medically treated asymptomatic carotid stenosis

MHF Poorthuis, Y Solomon, RAR Herings… - Stroke, 2023 - ahajournals.org
BACKGROUND: Effectiveness of carotid procedures (surgery and stenting) in patients with
asymptomatic carotid artery stenosis (ACAS) depends on the absolute risk reduction that …

Long-term stroke risk in patients with new ischemic brain lesions on MRI after carotid revascularization

SJA Donners, ML Rots, RJ Toorop, A van der Lugt… - Stroke, 2023 - ahajournals.org
BACKGROUND: Carotid artery revascularization can result in new ischemic brain lesions
on diffusion-weighted magnetic resonance imaging. This study aimed to investigate the …

Carotid endarterectomy in patients with recurrent symptoms associated with an ipsilateral carotid artery near occlusion with full collapse

AJA Meershoek, EPA Vonken, PJ Nederkoorn… - Journal of …, 2018 - Springer
Objective Near occlusion (NO) of the internal carotid artery (ICA) with full collapse (NOFC) is
a rare condition, with a prevalence of around 1%. Guidelines on carotid stenosis …

Prediction of severe baseline asymptomatic carotid stenosis and subsequent risk of stroke and cardiovascular disease

MHF Poorthuis, SHJ Hageman, ATL Fiolet, LJ Kappelle… - Stroke, 2024 - ahajournals.org
BACKGROUND: Risk models to identify patients at high risk of asymptomatic carotid artery
stenosis (ACAS) can help in selecting patients for screening, but long-term outcomes in these …

[HTML][HTML] Treatment of aneurysms of the extracranial carotid artery: current evidence and future perspectives

GJ De Borst, VEC Pourier - Journal of Neurology & Neuromedicine, 2016 - jneurology.com
Although very rare, aneurysms of the extracranial carotid artery (ECAA) are important to
identify and treat. Due to limitations in the literature consisting mostly of case reports and small …

[HTML][HTML] A nationwide analysis in France on sex difference and outcomes following carotid intervention in asymptomatic patients

F Lareyre, J Raffort, R Tulamo, GJ de Borst… - Journal of clinical …, 2024 - mdpi.com
Objective: The impact of sex on outcomes following carotid endarterectomy (CEA) and
carotid artery stenting (CAS) is not fully elucidated. The aim of this study was to analyze the …

Medical adjunctive therapy for patients with chronic limb-threatening ischemia: a systematic review

J Ipema, NC Roozendaal, WA Bax… - Journal of …, 2019 - research.rug.nl
INTRODUCTION: To systematically review the literature on medical adjunctive therapy for
patients with chronic limb-threatening ischemia (CLTI). EVIDENCE ACQUISITION: MEDLINE, …