… 36 Bots ML. Wall thickriess of the carotid artery as an indicator of generalized
atherosclerosis. The Rotterdam Study (Thesis). … 37 Bots ML. Witteman JCM. Grobbee DE. …

Background— Carotid intima-media thickness (IMT) is increasingly used as a surrogate marker
for atherosclerosis. Its use relies on its ability to predict future clinical cardiovascular end …

Context Imaging for subclinical atherosclerosis on top of conventional risk factor assessment
may improve risk prediction for the occurrence of cardiovascular disease events in …

Height is a highly heritable, classic polygenic trait with approximately 700 common associated
variants identified through genome-wide association studies so far. Here, we report 83 …

Cerebral white matter lesions are a common finding on MRI in elderly persons. We studied
the prevalence of white matter lesions and their relation with classic cardiovascular risk …

Background Noninvasive assessment of intima-media thickness (IMT) is widely used in
observational studies and trials as an intermediate or proxy end point for cardiovascular disease. …

Background Vascular disorders have been implicated in dementia, but whether atherosclerosis
is related to the most frequent type of dementia, Alzheimer's disease, is not known. The …

Background and Purpose—Studies of the association between arterial stiffness and
atherosclerosis are contradictory. We studied stiffness of the aorta and the common carotid artery in …

Background Ezetimibe, a cholesterol-absorption inhibitor, reduces levels of low-density
lipoprotein (LDL) cholesterol when added to statin treatment. However, the effect of ezetimibe on …

Elevated blood pressure is a common, heritable cause of cardiovascular disease worldwide.
To date, identification of common genetic variants influencing blood pressure has proven …