Gebruikersprofielen voor "Bronkhorst, A.J. "
![]() | Abel J. BronkhorstPostdoctoral researcher, German Heart Centre Munich Geverifieerd e-mailadres voor dhm.mhn.de Geciteerd door 2125 |
[HTML][HTML] The emerging role of cell-free DNA as a molecular marker for cancer management
AJ Bronkhorst, V Ungerer, S Holdenrieder - Biomolecular detection and …, 2019 - Elsevier
An increasing number of studies demonstrate the potential use of cell-free DNA (cfDNA) as
a surrogate marker for multiple indications in cancer, including diagnosis, prognosis, and …
a surrogate marker for multiple indications in cancer, including diagnosis, prognosis, and …
The diverse origins of circulating cell‐free DNA in the human body: a critical re‐evaluation of the literature
Since the detection of cell‐free DNA (cfDNA) in human plasma in 1948, it has been investigated
as a non‐invasive screening tool for many diseases, especially solid tumours and foetal …
as a non‐invasive screening tool for many diseases, especially solid tumours and foetal …
Putative origins of cell-free DNA in humans: a review of active and passive nucleic acid release mechanisms
S Grabuschnig, AJ Bronkhorst, S Holdenrieder… - International journal of …, 2020 - mdpi.com
Through various pathways of cell death, degradation, and regulated extrusion, partial or
complete genomes of various origins (eg, host cells, fetal cells, and infiltrating viruses and …
complete genomes of various origins (eg, host cells, fetal cells, and infiltrating viruses and …
[HTML][HTML] Characterization of the cell-free DNA released by cultured cancer cells
The most prominent factor that delays the translation of cell-free DNA (cfDNA) analyses to
clinical practice is the lack of knowledge regarding its origin and composition. The elucidation …
clinical practice is the lack of knowledge regarding its origin and composition. The elucidation …
Cell-free DNA: preanalytical variables
AJ Bronkhorst, J Aucamp, PJ Pretorius - Clinica Chimica Acta, 2015 - Elsevier
Since the discovery of cell-free DNA (cfDNA) in human blood, most studies have focused on
diagnostic and prognostic uses of these markers for solid tumors. Except for some prenatal …
diagnostic and prognostic uses of these markers for solid tumors. Except for some prenatal …
Harmonizing cell-free DNA collection and processing practices through evidence-based guidance
Circulating cell-free DNA (cfDNA) is rapidly transitioning from discovery research to an
important tool in clinical decision making. However, the lack of harmonization of preanalytic …
important tool in clinical decision making. However, the lack of harmonization of preanalytic …
New perspectives on the importance of cell-free DNA biology
AJ Bronkhorst, V Ungerer, A Oberhofer, S Gabriel… - Diagnostics, 2022 - mdpi.com
Body fluids are constantly replenished with a population of genetically diverse cell-free DNA
(cfDNA) fragments, representing a vast reservoir of information reflecting real-time changes …
(cfDNA) fragments, representing a vast reservoir of information reflecting real-time changes …
Towards systematic nomenclature for cell-free DNA
Cell-free DNA (cfDNA) has become widely recognized as a promising candidate biomarker
for minimally invasive characterization of various genomic disorders and other clinical …
for minimally invasive characterization of various genomic disorders and other clinical …
The clinical utility of droplet digital PCR for profiling circulating tumor DNA in breast cancer patients
U Gezer, AJ Bronkhorst, S Holdenrieder - Diagnostics, 2022 - mdpi.com
Breast cancer is the most common cancer affecting women worldwide. It is a malignant and
heterogeneous disease with distinct molecular subtypes, which has prognostic and …
heterogeneous disease with distinct molecular subtypes, which has prognostic and …
Preanalytical variables that affect the outcome of cell-free DNA measurements
V Ungerer, AJ Bronkhorst… - Critical Reviews in Clinical …, 2020 - Taylor & Francis
Fragments of cell-free DNA (cfDNA) in human body fluids often carry disease-specific alterations
and are now widely recognized as ideal biomarkers for the detection and monitoring of …
and are now widely recognized as ideal biomarkers for the detection and monitoring of …