The hypothalamo-neurohypophysial system (HNS) is the major peptidergic neurosecretory
system through which the brain controls peripheral physiology. The hormones vasopressin …

The cerebral cortex of Alzheimer's and Down syndrome patients is characterized by the
presence of protein deposits in neurofibrillary tangles, neuritic plaques, and neuropil threads. …

Dopaminergic neurons located in the ventral mesodiencephalon are essential for the
control of voluntary movement and the regulation of emotion, and are severely affected in …

Nurr1 is a member of the nuclear receptor superfamily of transcription factors that is
expressed predominantly in the central nervous system, including developing and mature …

We identified the LIM homeodomain transcription factor Lmx1b in the mesencephalic
dopamine (mesDA) systems of embryos and adults. Analysis of spatiotemporal expression in …

Forkhead transcription factors of the FoxO-group are associated with cellular processes like
cell cycle progression and DNA-repair. FoxO function is regulated by protein kinase B (PKB) …

The mesencephalic dopaminergic (mesDA) system regulates behavior and movement control
and has been implicated in psychiatric and affective disorders. We have identified a bicoid-…

The mesencephalic dopamine (mesDA) system is involved in the control of movement and
behavior. The expression of Pitx3 in the brain is restricted to the mesDA system and the gene …

A major advance in biomedical science and diagnosis was accomplished with the development
of in vivo techniques to image radiolabeled molecules, but limited spatial resolution has …

We know neuropeptides now for over 40 years as chemical signals in the brain. The discovery
of neuropeptides is founded on groundbreaking research in physiology, endocrinology, …