[HTML][HTML] Human plasma pregnancy-associated miRNAs and their temporal variation within the first trimester of pregnancy

C Légaré, AA Clément, V Desgagné… - Reproductive Biology …, 2022 - Springer
Background During pregnancy, maternal metabolism undergoes substantial changes to
support the developing fetus. Such changes are finely regulated by different mechanisms …

First trimester plasma microRNAs levels predict Matsuda Index-estimated insulin sensitivity between 24th and 29th week of pregnancy

C Légaré, V Desgagné, C Poirier, K Thibeault… - BMJ Open Diabetes …, 2022 - drc.bmj.com
Introduction Gestational diabetes mellitus (GDM) is a consequence of an imbalance between
insulin sensitivity (IS) and secretion during pregnancy. MicroRNAs (miRNAs) are small and …

[HTML][HTML] First trimester plasma MicroRNA levels predict risk of developing gestational diabetes mellitus

C Légaré, V Desgagné, K Thibeault, F White… - Frontiers in …, 2022 - frontiersin.org
Aims Our objective is to identify first-trimester plasmatic miRNAs associated with and predictive
of GDM. Methods We quantified miRNA using next-generation sequencing in discovery (…

[HTML][HTML] Maternal body mass index is associated with profile variation in circulating microRNAs at first trimester of pregnancy

K Thibeault, C Légaré, V Desgagné, F White… - Biomedicines, 2022 - mdpi.com
Many women enter pregnancy with overweight and obesity, which are associated with
complications for both the expectant mother and her child. MicroRNAs (miRNAs) are short non-…

Reporting on the 'ever closer union': narrative framing in national news medias and resistance to EU integration

AA Clement - Eastern journal of European studies, 2015 - ceeol.com
The implementation of the EU’s integrative policies has resulted in relatively recent resistance
to the integration process. Said popular politicization challenges further prospects for …

Comparing an adiposopathy approach with four popular classifications schemes to categorize the metabolic profile of postmenopausal women

P Mauriège, AD Karelis, N Taleb, AA Clément… - Journal of physiology …, 2020 - Springer
Numerous classifications are used to discern metabolically healthy obese (MHO) from
metabolically abnormal obese (MAO) individuals. The goal of this study was to compare a single …

The relationship between adiposopathy and glucose-insulin homeostasis is not affected by moderate-intensity aerobic training in healthy women with obesity

AA Clément, E Riesco, S Tessier, M Lacaille… - Journal of physiology …, 2018 - Springer
The contribution of adiposopathy to glucose-insulin homeostasis remains unclear. This
longitudinal study examined the potential relationship between the adiponectin/leptin ratio (A/L, a …

First trimester circulating miR-194-5p and miR-1278 improve prediction of preeclampsia

AA Clément, C Légaré, V Desgagné, K Thibeault… - Pregnancy …, 2023 - Elsevier
Objectives To identify first trimester circulating microRNAs associated with preeclampsia (PE)
and assess their predictive value in two independent cohorts Methods Circulating …

First-Trimester Plasmatic microRNAs Are Associated with Fasting Glucose Levels in Late Second Trimester of Pregnancy

C Légaré, V Desgagné, K Thibeault, F White… - Biomedicines, 2024 - mdpi.com
Maternal blood glucose regulation adaptation to pregnancy aims to support fetal growth but
may also lead to the development of gestational diabetes mellitus, the most common …

HDL-enriched miR-30a-5p is associated with HDL-cholesterol levels and glucose metabolism in healthy men and women

AA Clement, V Desgagne, C Legare, SP Guay… - …, 2021 - Taylor & Francis
Aim: To investigate the associations between high-density lipoprotein (HDL)-enriched miRNAs
and the cardiometabolic profile of healthy men and women. Patients & methods: miRNAs …