… Al-Janabi S, Huisman A & Van Diest PJ (2012) Histopathology 61, 1–9 …

This paper presents an overview of methods that have been proposed for the analysis of
breast cancer histopathology images. This research area has become particularly relevant with …

Breast cancer is the leading cause of death among solid tumours in women, and its
incidence is increasing in the West. Adjuvant chemotherapy and hormonal treatment improve …

Objectives Bone pain resulting from cancer metastases reduces a patient's quality of life.
Magnetic Resonance-guided High Intensity Focused Ultrasound (MR-HIFU) is a promising …

Background: The sentinel node (SN) concept assumes that early lymphatic metastases, if
present, always are found first in the SN. The aim of this study was to determine the reliability …

Background. Neoadjuvant chemotherapy improves survival in patients with locally advanced
breast cancer (LABC). Usually three to four cycles of conventional-dose neoadjuvant …

The hypoxia‐inducible factor 1 (HIF‐1) plays a critical role in cellular responses to hypoxia.
The aim of the present study was to evaluate which genes are induced by hypoxia, and …

Background: Sentinel node (SN) biopsy appears to offer an alternative to routine axillary lymph
node dissection (ALND) for staging patients with breast cancer. Various techniques have …

… de Jong JS, van Diest PJ, Baak JP. Hot spot microvessel density and the mitotic activity index
… Mommers EC, Poulin N, Meijer CJ, Baak JP, van Diest PJ. Malignancy-associated changes …

BACKGROUND Hypoxia‐inducible factor‐1 (HIF‐1) is a transcription factor that plays an
important role in tumor growth and metastasis by regulating energy metabolism and inducing …