Ulcerative colitis (UC) and Crohn's disease (CD), collectively known as Inflammatory Bowel
Diseases (IBD), are caused by a complex interplay between genetic, immunologic, microbial …

Angiotensin‐converting enzyme 2 (ACE2) has been established as the functional host
receptor for severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), the virus …

Inflammatory bowel disease (IBD) is associated with the production of reactive species that
target cysteine redox switches in proteins, thereby affecting gene regulation, DNA damage, …

Background and aims Proton pump inhibitors (PPIs) are among the top 10 most widely used
drugs in the world. PPI use has been associated with an increased risk of enteric infections, …

Objective The introduction of anti tumour necrosis factor-α (anti-TNFα) therapy might impact
healthcare expenditures, but there are limited data regarding the costs of inflammatory …

Background Human genetics and host-associated microbial communities have been associated
independently with a wide range of chronic diseases. One of the strongest associations …

Objective Patients with IBD display substantial heterogeneity in clinical characteristics. We
hypothesise that individual differences in the complex interaction of the host genome and the …

Objective The microbiome directly affects the balance of pro-inflammatory and anti-inflammatory
responses in the gut. As microbes thrive on dietary substrates, the question arises …

Changes in the gut microbiota have been associated with two of the most common gastrointestinal
diseases, inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS). Here…

A conformational study of some cinchona alkaloids is presented. The conformations of the
alkaloids in solution have been determined by NOE difference and NOESY NMR techniques. …