When, where and how is the head-tail axis of the embryo set up during development? These
are such fundamental and intensely studied questions that one might expect them to have …

ALL-trans retinoic acid (RA) is well known as a biologically active form of vitamin A and a
teratogen 1-8 . The identification of nuclear receptors for this ligand 9-11 suggests strongly that …

RETINOIDS (vitamin A and its metabolites) are suspected of regulating diverse aspects of
growth, differentiation, and patterning during embryogenesis 1 , but many questions remain …

Background The Hox genes are involved in patterning the anterior-posterior axis. In addition
to the protein coding Hox genes, the miR-10, miR-196 and miR-615 families of microRNA …

It is generally assumed that the characteristic deregionalized body plan of species with a
snake-like morphology evolved through a corresponding homogenization of Hox gene …

14 Jordan, IK et al.(2003) No simple dependence between protein evolution rate and the
number of protein–protein interactions: only the most prolific interactors tend to evolve slowly. …

The Hox paralogous group 1 (PG1) genes are the first and initially most anterior Hox genes
expressed in the embryo. In Xenopus, the three PG1 genes, Hoxa1, Hoxb1 and Hoxd1, are …

Here, we review a recently discovered developmental mechanism. Anterior–posterior
positional information for the vertebrate trunk is generated by sequential interactions between a …

We report a novel developmental mechanism. Anterior–posterior positional information for
the vertebrate trunk is generated by sequential interactions between a timer in the early non-…

We made mixed mounds of vitally stained prestalk cells and unstained prespore cells, from
Dictyostelium discoideum (Dd), and exposed these to external 3′,5′-cyclic-AMP (c-AMP) …