Immune responses to certain heat-shock proteins (HSPs) develop in almost all inflammatory
diseases; however, the significance of such responses is only now becoming clear. In …

Immune responses to heat shock proteins (Hsp) develop in virtually all inflammatory diseases;
however, the significance of such responses is only now becoming clear. In experimental …

The significance of immune responses to certain heat shock proteins (HSPs) that develop in
virtually all inflammatory diseases is only now becoming clear. In experimental models, …

Objective— HSP60-specific T cells contribute to the development of the immune responses
in atherosclerosis. This can be dampened by regulatory T cells activated via oral tolerance …

Background— Oxidation of low-density lipoprotein (LDL) and the subsequent processing of
oxidized LDL (oxLDL) by macrophages results in activation of specific T cells, which …

A postulated mechanism for autoimmune disorders is that the immunoreactivity develops
against bacterial antigens which show a high degree of sequence homology with mammalian …

Bovine paratuberculosis is caused by infection of young calves withMycobacterium avium
subsp. paratuberculosis. In some of the chronically infected cows the long asymptomatic stage …

Development of vaccines in autoimmune diseases has received wide attention over the last
decade. However, many vaccines showed limited clinical efficacy. To enhance vaccine …

Objective. To determine whether T lymphocyte reactivity to endogenous human hsp60 plays
a regulatory role in the course of oligoarticular juvenile rheumatoid arthritis (JRA). Methods. …

The fundamental problem of autoimmune diseases is the failure of the immune system to
downregulate its own potentially dangerous cells, which leads to destruction of tissue …