ADRs can be classified using the WHO adverse reaction terminology [11]. According to this,
ADRs are divided into 32 system-organ classes (eg skin). The class forms the first part of the …

CONTEXT. Pediatric and intensive care patients are particularly at risk for medication errors.
Computerized physician order entry systems could be effective in reducing medication …

Adverse drug effects are manifold and heterogenous. Many situations may hamper the
signalling (ie the detection of early warning signs) of adverse effects and new signals often differ …

… In: Egberts ACG, editor. Pharmacoepidemiologic approaches to the evaluation of antidepressant
drugs. Utrecht: Utrecht University, Faculty of Pharmacy, 1997: 112-24 …

Background Medication-related problems that lead to hospitalization have been the subject
of many studies, many of which were limited to 1 hospital or lacked patient follow-up. …

Purpose A continuous systematic review of all combinations of drugs and suspected adverse
reactions (ADRs) reported to a spontaneous reporting system, is necessary to optimize …

Objective: To assess whether use of oral glucocorticoids is associated with cardiovascular
and cerebrovascular morbidity. Design and setting: Nested case–control study within a cohort …

Purpose Several preclinical studies suggested a role for 3-hydroxy-3-methylglutaryl-coenzyme
A reductase inhibitors (statins) in the treatment of cancer. The objective of this study was …

The driving performance is easily impaired as a consequence of the use of alcohol and/or
licit and illicit drugs. However, the role of drugs other than alcohol in motor vehicle accidents …

WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT • Polypharmacy is common among the
elderly. • Underprescribing is also frequent. • Optimizing polypharmacy includes avoiding …