Cognition and synaptic plasticity in diabetes mellitus

WH Gispen, GJ Biessels - Trends in neurosciences, 2000 - cell.com
Diabetes mellitus is associated with cognitive deficits and an increased risk of dementia,
particularly in the elderly. These deficits are paralleled by neurophysiological and structural …

Cerebral function in diabetes mellitus

GJ Biessels, AC Kappelle, B Bravenboer, DW Erkelens… - Diabetologia, 1994 - Springer
Diabetes mellitus is a common metabolic disorder associated with chronic complications such
as nephropathy, angiopathy, retinopathy and peripheral neuropathy. Diabetes is not often …

Ethology and neurobiology of grooming behavior

BM Spruijt, JA Van Hooff… - Physiological reviews, 1992 - journals.physiology.org
The outer body surface of animals is complex and appears in a variety of forms from moist or
slimy, dry, soft, and leathery to hard, horny, or bony. The skin is often equipped with devices…

Ageing and diabetes: implications for brain function

GJ Biessels, LP van der Heide, A Kamal… - European journal of …, 2002 - Elsevier
Diabetes mellitus is associated with moderate cognitive deficits and neurophysiological and
structural changes in the brain, a condition that may be referred to as diabetic …

Automated quantitative gait analysis during overground locomotion in the rat: its application to spinal cord contusion and transection injuries

FPT Hamers, AJ Lankhorst, TJ van Laar… - Journal of …, 2001 - liebertpub.com
Analysis of locomotion is an important tool in the study of peripheral and central nervous
system damage. Most locomotor scoring systems in rodents are based either upon open field …

Place learning and hippocampal synaptic plasticity in streptozotocin-induced diabetic rats

GJ Biessels, A Kamal, GM Ramakers, IJ Urban… - Diabetes, 1996 - Am Diabetes Assoc
Moderate impairment of learning and memory has been recognized as a complication of
diabetes. The present study examined behavioral and electrophysiological measures of …

Water maze learning and hippocampal synaptic plasticity in streptozotocin-diabetic rats: effects of insulin treatment

GJ Biessels, A Kamal, IJA Urban, BM Spruijt… - Brain research, 1998 - Elsevier
Streptozotocin-diabetic rats express deficits in water maze learning and hippocampal synaptic
plasticity. The present study examined whether these deficits could be prevented and/or …

Injury-induced class 3 semaphorin expression in the rat spinal cord

F De Winter, M Oudega, AJ Lankhorst, FP Hamers… - Experimental …, 2002 - Elsevier
In this study we evaluate the expression of all members of the class 3 semaphorins and their
receptor components following complete transection and contusion lesions of the adult rat …

Long‐lasting modulation of the induction of LTD and LTP in rat hippocampal CA1 by behavioural stress and environmental enrichment

A Artola, JC Von Frijtag, PCJ Fermont… - European Journal of …, 2006 - Wiley Online Library
Behavioural experience (eg chronic stress, environmental enrichment) can have long‐lasting
effects on cognitive functions. Because activity‐dependent persistent changes in synaptic …

[HTML][HTML] Phosphatidic acid is a specific activator of phosphatidylinositol-4-phosphate kinase.

A Moritz, PN De Graan, WH Gispen, KW Wirtz - Journal of Biological …, 1992 - Elsevier
The lipid dependence of phosphatidylinositol-4-phosphate (PIP) kinase purified from bovine
brain membranes was investigated. In the assay used, PIP-Triton X-100 micelles containing …