Glomerular endothelial injury plays an important role in the pathogenesis of renal diseases
and is centrally involved in renal disease progression. Glomerular endothelial repair may …

We have reviewed the literature in order to delineate the clinicopathologic definition of orbital
pseudotumor, also called idiopathic nonspecific orbital inflammation. The clinical picture of …

Connective tissue growth factor (CTGF) has recently received much attention as a possible
key determinant of progressive fibrosis and excessive scarring and also of wound repair, …

Fibrosis is the common end point of chronic kidney disease. The persistent production of
inflammatory cytokines and growth factors leads to an ongoing process of extracellular matrix …

Expression of connective tissue growth factor in human renal fibrosis. Chronic renal failure
may occur in etiologically diverse renal diseases and can be caused by hemodynamic, …

Vasculitis is a rare complication of propylthiouracil therapy. Antineutrophil cytoplasmic
antibodies (ANCA) have been described in association with several vasculitic disorders. We …

A proposal is put forth to unify the nomenclature of the CCN family of secreted, cysteine rich
regulatory proteins. In the order of their description in the literature, CCN1 (CYR61), CCN2 (…

Anti-neutrophil cytoplasmic autoantibodies (ANCA) specifically associated with Wegener's
granulomatosis were found to be directed against a saline-soluble glycoprotein triplet that …

Mutations in APC or β-catenin inappropriately activate the transcription factor Tcf4, thereby
transforming intestinal epithelial cells. Here it is shown that one of the target genes of Tcf4 in …

Chronic kidney disease (CKD) represents a major health burden 1 . Its central feature of renal
fibrosis is not well understood. By exome sequencing, we identified mutations in FAN1 as …