The skin has long been recognized as a major producer of cytokines, but the keratinocyte
as principal epidermal cell has received less attention as potential source and target of …

The virulence of Clostridium perfringens, a bacterium causing enteritis and enterotoxaemia
in domestic and wild animals and humans, results largely from its ability to produce toxins. In …

Clostridium perfringens is one of the major causes of intestinal disease in humans and
animals. Its pathogenicity is contributed to by the production of a variety of toxins. In addition, …

Hypothesis: Certain variables that are routinely measured during the diagnostic evaluation
of dogs with chronic enteropathies will be predictive for outcome and a new clinical disease …

Epidermal growth factor receptor (EGFR) is known to be critically involved in tissue development
and homeostasis as well as in the pathogenesis of cancer. Here we showed that Foxp3 …

Stable Foxp3 expression is required for the development of functional regulatory T (Treg)
cells. Here, we demonstrate that the expression of the transcription factor Foxp3 can be …

In dit jaarrapport worden de resultaten gepresenteerd van pathologisch onderzoek aan
bruinvissen in 2019. Eén van de hoofddoelen van het onderzoek is het kwantificeren van sterfte …

Foxp3 is crucial for both the development and function of regulatory T (Treg) cells; however,
the posttranslational mechanisms regulating Foxp3 transcriptional output remain poorly …

The binding of viruses to host cells is the first step in determining tropism and pathogenicity.
While avian infectious bronchitis coronavirus (IBV) infection and avian influenza A virus (IAV…

The usual treatment of dogs with inflammatory bowel disease (IBD) consists of administration
of immunosuppressive doses of steroids. However, some dogs are refractory to steroid …