Antimicrobial host defence peptides: functions and clinical potential
Cationic host defence peptides (CHDP), also known as antimicrobial peptides, are naturally
occurring peptides that can combat infections through their direct microbicidal properties and…
occurring peptides that can combat infections through their direct microbicidal properties and…
The pulmonary surfactant system: biochemical and clinical aspects
L Creuwels, LMG Van Golde, HP Haagsman - Lung, 1997 - Springer
This article starts with a brief account of the history of research on pulmonary surfactant. We
will then discuss the morphological aspects and composition of the pulmonary surfactant …
will then discuss the morphological aspects and composition of the pulmonary surfactant …
[HTML][HTML] Role of pulmonary surfactant components in surface film formation and dynamics
EJA Veldhuizen, HP Haagsman - Biochimica et biophysica acta (bba) …, 2000 - Elsevier
Pulmonary surfactant is a mixture of lipids and proteins which is secreted by the epithelial
type II cells into the alveolar space. Its main function is to reduce the surface tension at the air/…
type II cells into the alveolar space. Its main function is to reduce the surface tension at the air/…
Reduced airway surface pH impairs bacterial killing in the porcine cystic fibrosis lung
AA Pezzulo, XX Tang, MJ Hoegger, MH Abou Alaiwa… - Nature, 2012 - nature.com
Cystic fibrosis (CF) is a life-shortening disease caused by mutations in the cystic fibrosis
transmembrane conductance regulator (CFTR) gene 1 . Although bacterial lung infection and …
transmembrane conductance regulator (CFTR) gene 1 . Although bacterial lung infection and …
Carvacrol Induces Heat Shock Protein 60 and Inhibits Synthesis of Flagellin in Escherichia coli O157:H7
SA Burt, R van der Zee, AP Koets… - Applied and …, 2007 - Am Soc Microbiol
The essential oils of oregano and thyme are active against a number of food-borne
pathogens, such as Escherichia coli O157:H7. Carvacrol is one of the major antibacterial …
pathogens, such as Escherichia coli O157:H7. Carvacrol is one of the major antibacterial …
Structural requirements for the antimicrobial activity of carvacrol
EJA Veldhuizen… - Journal of agricultural …, 2006 - ACS Publications
Carvacrol is a component of several essential oils and has been shown to exert antimicrobial
activity. The structural requirements for the activity of carvacrol were determined by …
activity. The structural requirements for the activity of carvacrol were determined by …
Increase in activity of essential oil components carvacrol and thymol against Escherichia coli O157: H7 by addition of food stabilizers
SA Burt, R Vlielander, HP Haagsman… - Journal of food …, 2005 - Elsevier
The major components of oregano and thyme essential oils that had previously been shown
to inhibit Escherichia coli O157:H7 were determined by high-performance liquid …
to inhibit Escherichia coli O157:H7 were determined by high-performance liquid …
Pulmonary surfactant protein A enhances the host-defense mechanism of rat alveolar macrophages
F van Iwaarden, B Welmers, J Verhoef… - Am J Respir Cell Mol …, 1990 - atsjournals.org
In 1973, La Force and associates (1) reported enhanced killing ofStaphylococcus aureus by
alveolar macrophages in the presence of surfactant and postulated a role fur surfactant in …
alveolar macrophages in the presence of surfactant and postulated a role fur surfactant in …
Surfactant-associated proteins: functions and structural variation
HP Haagsman, RV Diemel - … Biochemistry and Physiology Part A: Molecular …, 2001 - Elsevier
Pulmonary surfactant is a barrier material of the lungs and has a dual role: firstly, as a true
surfactant, lowering the surface tension; and secondly, participating in innate immune defence …
surfactant, lowering the surface tension; and secondly, participating in innate immune defence …
Avian defensins
A van Dijk, EJA Veldhuizen, HP Haagsman - Veterinary Immunology and …, 2008 - Elsevier
Modulation of defensin expression may be one way to improve animal health and to reduce
zoonotic diseases. Defensins are small, cationic, and amphipathic cysteine-rich antibiotic …
zoonotic diseases. Defensins are small, cationic, and amphipathic cysteine-rich antibiotic …