[HTML][HTML] Neural networks for survival prediction in medicine using prognostic factors: a review and critical appraisal

G Kantidakis, AD Hazewinkel, M Fiocco - … and Mathematical Methods …, 2022 - hindawi.com
Survival analysis deals with the expected duration of time until one or more events of interest
occur. Time to the event of interest may be unobserved, a phenomenon commonly known …

Response and side effects using stimulant medication in older adults with ADHD: an observational archive study

M Michielsen, D Kleef, D Bijlenga… - Journal of Attention …, 2021 - journals.sagepub.com
Objective: To examine the naturalistic response to and cardiovascular side effects of stimulant
medication in older adults with ADHD. Methods: Electronic Health Record (EHR) data of …

The incidence and economic impact of aggression in closed long-stay psychiatric wards

NJ de Bles, AWP Hazewinkel… - … journal of psychiatry …, 2021 - Taylor & Francis
Objective Aggressive behaviour is highly prevalent in long-term psychiatric inpatient care.
We aimed to estimate the overall incidence of aggression, the time staff took to handle …

Add-on filgrastim during clozapine rechallenge unsuccessful in preventing agranulocytosis

AWP Hazewinkel, JPAM Bogers, EJ Giltay - General hospital psychiatry, 2013 - Elsevier
Granulocyte colony-stimulating factor agents such as filgrastim can be administered in order
to reduce the duration of clozapine-induced agranulocytosis. Successful long-term …

Sensitivity to missing not at random dropout in clinical trials: Use and interpretation of the trimmed means estimator

AD Hazewinkel, J Bowden, KH Wade… - Statistics in …, 2022 - Wiley Online Library
Outcome values in randomized controlled trials (RCTs) may be missing not at random (MNAR),
if patients with extreme outcome values are more likely to drop out (eg, due to perceived …

Developmental patterns in self-analytic groups

BC Kuypers, D Davies, A Hazewinkel - Human Relations, 1986 - journals.sagepub.com
This study outlines and tests a dialectical model of group development in self-analytic training
groups. Part 1 establishes dimensions that differentiate between developmental phases …

[HTML][HTML] Mendelian randomization analysis of the causal impact of body mass index and waist-hip ratio on rates of hospital admission

AD Hazewinkel, RC Richmond, KH Wade… - Economics & Human …, 2022 - Elsevier
We analyze how measures of adiposity – body mass index (BMI) and waist hip ratio (WHR)
– causally influence rates of hospital admission. Conventional analyses of this relationship …

Prediction models with survival data: a comparison between machine learning and the Cox proportional hazards model

AD Hazewinkel, H Gelderblom, M Fiocco - medRxiv, 2022 - medrxiv.org
Recent years have seen increased interest in using machine learning (ML) methods for
survival prediction, chiefly using big datasets with mixed datatypes and/or many predictors …

Treatment group outcome variance difference after dropout as an indicator of missing-not-at-random bias in randomized clinical trials

AD Hazewinkel, K Tilling, KH Wade, T Palmer - medRxiv, 2022 - medrxiv.org
Randomized controlled trials (RCTs) are considered the gold standard for assessing the causal
effect of an exposure on an outcome, but are vulnerable to bias from missing data. When …

[HTML][HTML] Short-term effects of electroconvulsive therapy on subjective and actigraphy-assessed sleep parameters in severely depressed inpatients

A Hoogerhoud, AWP Hazewinkel… - Depression research …, 2015 - hindawi.com
Background. Sleep disturbances are a key feature of major depression. Electroconvulsive
treatment (ECT) may improve polysomnography-assessed sleep characteristics, but its short-…