Medetomidine and dexmedetomidine: a review of cardiovascular effects and antinociceptive properties in the dog

JC Murrell, LJ Hellebrekers - Veterinary anaesthesia and analgesia, 2005 - Elsevier
Alpha 2 -adrenoreceptor agonists (α 2 -agonists) are commonly used in small animal
anaesthesia for their potent sedative and analgesic properties, although concerns about their …

Indicators used in livestock to assess unconsciousness after stunning: a review

MTW Verhoeven, MA Gerritzen, LJ Hellebrekers… - Animal, 2015 - cambridge.org
Assessing unconsciousness is important to safeguard animal welfare shortly after stunning
at the slaughter plant. Indicators that can be visually evaluated are most often used when …

Application of a modified form of the Glasgow pain scale in a veterinary teaching centre in the Netherlands

JC Murrell, EP Psatha, EM Scott, J Reid… - Veterinary …, 2008 - Wiley Online Library
The Glasgow Composite Measure Pain Scale was developed to measure acute pain in dogs
in a hospital setting. In this investigation a modified version of the scale was applied in a …

Effects of intravenous lidocaine on isoflurane concentration, physiological parameters, metabolic parameters and stress‐related hormones in horses undergoing …

TB Dzikiti, LJ Hellebrekers… - Journal of Veterinary …, 2003 - Wiley Online Library
Physiological parameters, metabolic parameters and stress‐related hormones are evaluated
in horses anaesthetized with isoflurane in oxygen combined with lidocaine intravenously. …

Dexmedetomidine continuous rate infusion during isoflurane anaesthesia in canine surgical patients

JJ Uilenreef, JC Murrell, BC McKusick… - Veterinary anaesthesia …, 2008 - Elsevier
Objective To determine the effects of three rates of dexmedetomidine (DMED) constant rate
infusion (CRI) on overall tissue perfusion, isoflurane (ISO) requirements, haemodynamics …

Effects of a local anaesthetic and NSAID in castration of piglets, on the acute pain responses, growth and mortality

M Kluivers-Poodt, BB Houx, SRM Robben, G Koop… - Animal, 2012 - Elsevier
The present study addresses the questions whether on-farm use of local anaesthesia with
lidocaine leads to a reduction in pain responses during castration, and whether the non-…

Application of a composite pain scale to objectively monitor horses with somatic and visceral pain under hospital conditions

JPAM van Loon, W Back, LJ Hellebrekers… - Journal of Equine …, 2010 - Elsevier
Pain recognition and management in animals has advanced considerably in the last
decade and currently animal welfare is receiving increasing public interest. However, the …

Clinical evaluation of the efficacy and safety of a constant rate infusion of dexmedetomidine for postoperative pain management in dogs

C Valtolina, JH Robben, J Uilenreef, JC Murrell… - Veterinary Anaesthesia …, 2009 - Elsevier
Objective To compare postoperative analgesia provided by a constant rate infusion (CRI) of
dexmedetomidine (DMED) to that of a well-established positive control [morphine (MOR)] in …

Dexmedetomidine constant rate infusion for 24 hours during and after propofol or isoflurane anaesthesia in dogs

GY Lin, JH Robben, JC Murrell, J Aspegrén… - Veterinary Anaesthesia …, 2008 - Elsevier
Objective To evaluate cardiovascular and respiratory effects and pharmacokinetics of a 24-hour
intravenous constant rate infusion (CRI) of dexmedetomidine (DMED) during and after …

Pain behaviour after castration of piglets; effect of pain relief with lidocaine and/or meloxicam

M Kluivers-Poodt, JJ Zonderland, J Verbraak… - Animal, 2013 - Elsevier
Behavioural responses and the effect of lidocaine and meloxicam on behaviour of piglets
after castration were studied. A total of 144 piglets of 2 to 5 days of age were allocated to one …