Drug targeting systems are nanometre-sized carrier materials designed for improving the
biodistribution of systemically applied (chemo) therapeutics. Various different tumour-targeted …

Nanomedicine formulations aim to improve the biodistribution and the target site
accumulation of systemically administered (chemo)therapeutic agents. Many different types of …

With advances in tissue engineering, the possibility of regenerating injured tissue or failing
organs has become a realistic prospect for the first time in medical history. Tissue …

Over the past decades, significant progress has been made in the field of hydrogels as
functional biomaterials. Biomedical application of hydrogels was initially hindered by the toxicity …

In this review the current knowledge of protein degradation during preparation, storage and
release from poly(lactic-co-glycolic acid) (PLGA) microparticles is described, as well as …

Curcumin, a natural yellow phenolic compound, is present in many kinds of herbs,
particularly in Curcuma longa Linn. (turmeric). It is a natural antioxidant and has shown many …

The hydrolytic degradation of monodisperse lactic acid oligomers was studied in vitro to
gain insight into the degradation of oligolactic acid grafted to dextran, which we use for the …

Hydrogels are presently under investigation as matrices for the controlled release of bioactive
molecules, in particular pharmaceutical proteins, and for the encapsulation of living cells. …

Many different systems and strategies have been evaluated for drug targeting to tumors over
the years. Routinely used systems include liposomes, polymers, micelles, nanoparticles …

Reduction-sensitive biodegradable polymers and conjugates have emerged as a fascinating
class of biomedical materials that can be elegantly applied for intracellular triggered gene …