In this paper we explore the impact of new levels ofselection in models of early evolution.We
contrast two types of higher levels of selection. On the one hand we look at spatially …

We review computational studies on prebiotic evolution, focusing on informatic processes in
RNA-like replicator systems. In particular, we consider the following processes: the …

Understanding how genotypes map onto phenotypes, fitness, and eventually organisms is
arguably the next major missing piece in a fully predictive theory of evolution. We refer to this …

The plant growth regulator auxin controls cell identity, cell division and cell expansion. Auxin
efflux facilitators (PINs) are associated with auxin maxima in distal regions of both shoots …

In the study of pre-biotic evolution self-structuring and evolutionary processes are themes that
are usually studied separately. In this paper we demonstrate that spatial self-structuring in …

From the late 1980s onward, the term “bioinformatics” mostly has been used to refer to
computational methods for comparative analysis of genome data. However, the term was …

Lateral organ position along roots and shoots largely determines plant architecture, and
depends on auxin distribution patterns. Determination of the underlying patterning mechanisms …

… Science 209:457-463 Hogeweg P (1976a) Iterative character weighting in numerical
taxonomy. Comput Biol Med 6:166-211 Hogeweg P (1976b) Topics in biological pattern analysis. …

We review cellular automata as a modeling formalism and discuss how it can be used for
modeling (spatial) ecological processes. The implications of this modeling paradigm for …

We present a three-dimensional hybrid cellular automata (CA)/partial differential equation (PDE)
model that allows for the study of morphogenesis in simple cellular systems. We apply …