Purpose: The aim of this survey was to review the different studies regarding the occurrence
of second primary tumors (SPT) among survivors of retinoblastoma. Methods: Ovid (Medline…

Purpose To determine the age-specific incidence and prevalence of keratoconus in the modern
era of diagnostics. Design Epidemiologic study. Participants Total of 4.4 million patients …

Every year, 3000 women in the Netherlands are treated with in-vitro fertilisation (IVF), and
results from studies suggest that the offspring of these women do not have a heightened risk of …

The aim of this paper is to summarize all available evidence from systematic reviews,
randomized controlled trials (RCTs) and comparative nonrandomized studies (NRS) on the …

Background Survivors of hereditary retinoblastoma have an elevated risk of developing
second malignancies, but data on the risk in middle-aged retinoblastoma survivors (ie, those …

Herpesviruses infect the majority of the human population and can cause significant morbidity
and mortality. Herpes simplex virus (HSV) type 1 causes cold sores and herpes simplex …

Childhood craniopharyngioma is a rare and slow growing brain tumour, often located in the
sellar and suprasellar region. It commonly manifests with visual impairment, increased …

Purpose To compare the clinical effects and safety of transepithelial corneal cross-linking (CXL)
to epithelium-off (epi-off) CXL in progressive keratoconus. Design Randomized clinical …

AIM The aim of this study was to determine the (time trends in) incidence and survival of
hereditary (familial and sporadic) and non-hereditary retinoblastoma for male and female …

OBJECTIVE: The aim of this study is to evaluate the influence of age at external beam
irradiation (EBRT) on the occurrence of second primary tumors (SPTs) inside and outside the …