Prediction of pharmacokinetic alterations caused by drug-drug interactions: metabolic interaction in the liver
K Ito, T Iwatsubo, S Kanamitsu, K Ueda, H Suzuki… - Pharmacological …, 1998 - ASPET
Serious side-effects caused by drug interactions have attracted a great deal of attention and
have become a social problem since the coadministration of ketoconazole and terfenadine …
have become a social problem since the coadministration of ketoconazole and terfenadine …
[HTML][HTML] Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in …
P Godoy, NJ Hewitt, U Albrecht, ME Andersen… - Archives of …, 2013 - Springer
This review encompasses the most important advances in liver functions and hepatotoxicity
and analyzes which mechanisms can be studied in vitro. In a complex architecture of nested, …
and analyzes which mechanisms can be studied in vitro. In a complex architecture of nested, …
Histone acetylation and deacetylation: importance in inflammatory lung diseases
… Cosio BG, Mann B, Ito K, et al. Histone acetylase and deacetylase activity in alveolar
macrophages and blood monocytes in asthma. Am J Respir Crit Care Med 2004;170:141–147. …
macrophages and blood monocytes in asthma. Am J Respir Crit Care Med 2004;170:141–147. …
The super-kamiokande detector
S Fukuda, Y Fukuda, T Hayakawa, E Ichihara… - Nuclear Instruments and …, 2003 - Elsevier
Super-Kamiokande is the world's largest water Cherenkov detector, with net mass 50,000
tons. During the period April, 1996 to July, 2001, Super-Kamiokande I collected 1678 live-days …
tons. During the period April, 1996 to July, 2001, Super-Kamiokande I collected 1678 live-days …
Pressure-Induced Superconductivity in Noncentrosymmetric Heavy-Fermion
N Kimura, K Ito, K Saitoh, Y Umeda, H Aoki… - Physical review …, 2005 - APS
We report the pressure-induced superconductivity in the noncentrosymmetric heavy-fermion
CeRhSi 3 . The superconductivity emerges above about 12 kbar even though the …
CeRhSi 3 . The superconductivity emerges above about 12 kbar even though the …
Solar neutrino measurements in Super-Kamiokande-IV
K Abe, Y Haga, Y Hayato, M Ikeda, K Iyogi, J Kameda… - Physical Review D, 2016 - APS
Upgraded electronics, improved water system dynamics, better calibration and analysis
techniques allowed Super-Kamiokande-IV to clearly observe very low-energy B 8 solar neutrino …
techniques allowed Super-Kamiokande-IV to clearly observe very low-energy B 8 solar neutrino …
Discrimination between Alzheimer dementia and controls by automated analysis of multicenter FDG PET
A new diagnostic indicator of FDG PET scan abnormality, based on age-adjusted t statistics
and an automated voxel-based procedure, is presented and validated in a large data set …
and an automated voxel-based procedure, is presented and validated in a large data set …
Cigarette smoking reduces histone deacetylase 2 expression, enhances cytokine expression, and inhibits glucocorticoid actions in alveolar macrophages
Cigarette smoke is the major cause of chronic obstructive pulmonary disease (COPD), a
chronic inflammatory disease of the airway. The increased expression of inflammatory proteins …
chronic inflammatory disease of the airway. The increased expression of inflammatory proteins …
High-temperature structural intermetallics
M Yamaguchi, H Inui, K Ito - Acta materialia, 2000 - Elsevier
In the last one and a half decades, a great deal of fundamental and developmental research
has been made on high-temperature structural intermetallics aiming at the implementation …
has been made on high-temperature structural intermetallics aiming at the implementation …
A cross-population atlas of genetic associations for 220 human phenotypes
Current genome-wide association studies do not yet capture sufficient diversity in
populations and scope of phenotypes. To expand an atlas of genetic associations in non-European …
populations and scope of phenotypes. To expand an atlas of genetic associations in non-European …
