In plasma, a significant part of suramin circulates in tight association with low-density lipoproteins
(LDL). At therapeutically obtainable concentrations (100 μM) of suramin, about 85% of …

By considering all possible mutations among four para-substituted phenols, p-chlorophenol,
p-methylphenol, p-cyanophenol, and p-methoxyphenol, which bind as inclusion …

In order to obtain a better understanding of the neutral-to-base (NB) transition of human
serum albumin, we performed acid/base titration experiments and 500-MHz 1 H NMR …

The reductive activation of mitosene compounds was studied with cyclic voltammetry and
HPLC analysis. Reduction of mitosenes, possessing good leaving groups at Cl and C-10, was …

Relationships between the antimicrobial activities of sulfonamides and physico‐chemical
properties including the acid dissociation constant (pK a ) and the hydrophobicity constant (π) …

Revised Manuscript Received February 2, 1993 abstract: The role of electrostatics in the
adsorption process of proteins to preformed negatively-charged (phosphatidylcholine/…

… Bos OJM, Fischer MJE, Wilting J and Janssen LHM, Drug binding and other … Wilting J, van
der Giesen WF and Janssen LHM, The effect of chloride on the binding of warfarin to albumin …

pK change of imidazole groups in bovine serum albumin due to the conformational change at
neutral pH Page 1 IMIDAZOLE GROUPS IN SERUM ALBUMIN and Blout, E. R. (1971), J. Amer …

The diazepam-binding behaviour of a large tryptic and a large peptic fragment of human
serum albumin has been studied by circular dichroism and equilibrium dialysis in order to …

The concept of bioreductive alkylation as a mechanism of action of aziridinylquinoid
anticancer agents has been investigated by the use of electrochemical techniques. Properly …