Background A combination of general anesthesia (GA) with thoracic epidural anesthesia (TEA)
may have a beneficial effect on clinical outcomes after cardiac surgery. We have …

Background— Several models have been developed to predict prolonged stay in the intensive
care unit (ICU) after cardiac surgery. However, no extensive quantitative validation of …

Background High‐dose prophylactic corticosteroids are often administered during cardiac
surgery. Their use, however, remains controversial, as no trials are available that have been …

Background Selective digestive tract decontamination (SDD) and selective oropharyngeal
decontamination (SOD) are infection-prevention measures used in the treatment of some …

We developed and validated a prediction rule for the occurrence of early postoperative
severe pain in surgical inpatients, using predictors that can be easily documented in a …

Background: Severe pain after surgery remains a major problem, occurring in 20–40% of
patients. Despite numerous published studies, the degree of pain following many types of …

Objective: To evaluate the effect of implementation of the WHO's Surgical Safety Checklist
on mortality and to determine to what extent the potential effect was related to checklist …

Background Cut-off points (CPs) of the numeric rating scale (NRS 0–10) are regularly used
in postoperative pain treatment. However, there is insufficient evidence to identify the optimal …

Background Intraoperative hypotension (IOH) is a common side effect of general anesthesia
and has been reported to be associated with adverse perioperative outcomes. These …

ContextCoronary artery bypass graft (CABG) surgery is associated with a decline in
cognitive function, which has largely been attributed to the use of cardiopulmonary bypass (on-pump …