Gebruikersprofielen voor "Kapitein, L.C. "
Lukas C. KapiteinUtrecht University Geverifieerd e-mailadres voor uu.nl Geciteerd door 11600 |
Building the neuronal microtubule cytoskeleton
LC Kapitein, CC Hoogenraad - Neuron, 2015 - cell.com
Microtubules are one of the major cytoskeletal components of neurons, essential for many
fundamental cellular and developmental processes, such as neuronal migration, polarity, and …
fundamental cellular and developmental processes, such as neuronal migration, polarity, and …
Mechanisms of microtubule organization in differentiated animal cells
A Akhmanova, LC Kapitein - Nature Reviews Molecular Cell Biology, 2022 - nature.com
Microtubules are polarized cytoskeletal filaments that serve as tracks for intracellular
transport and form a scaffold that positions organelles and other cellular components and …
transport and form a scaffold that positions organelles and other cellular components and …
[HTML][HTML] Which way to go? Cytoskeletal organization and polarized transport in neurons
LC Kapitein, CC Hoogenraad - Molecular and Cellular Neuroscience, 2011 - Elsevier
To establish and maintain their polarized morphology, neurons employ active transport driven
by cytoskeletal motor proteins to sort cargo between axons and dendrites. These motors …
by cytoskeletal motor proteins to sort cargo between axons and dendrites. These motors …
The bipolar mitotic kinesin Eg5 moves on both microtubules that it crosslinks
During cell division, mitotic spindles are assembled by microtubule-based motor proteins 1 ,
2 . The bipolar organization of spindles is essential for proper segregation of chromosomes, …
2 . The bipolar organization of spindles is essential for proper segregation of chromosomes, …
Dynamic microtubules regulate dendritic spine morphology and synaptic plasticity
J Jaworski, LC Kapitein, SM Gouveia, BR Dortland… - Neuron, 2009 - cell.com
Dendritic spines are the major sites of excitatory synaptic input, and their morphological
changes have been linked to learning and memory processes. Here, we report that growing …
changes have been linked to learning and memory processes. Here, we report that growing …
Microtubule stabilization reduces scarring and causes axon regeneration after spinal cord injury
F Hellal, A Hurtado, J Ruschel, KC Flynn, CJ Laskowski… - Science, 2011 - science.org
Hypertrophic scarring and poor intrinsic axon growth capacity constitute major obstacles for
spinal cord repair. These processes are tightly regulated by microtubule dynamics. Here, …
spinal cord repair. These processes are tightly regulated by microtubule dynamics. Here, …
TRAK/Milton motor-adaptor proteins steer mitochondrial trafficking to axons and dendrites
M van Spronsen, M Mikhaylova, J Lipka, MA Schlager… - Neuron, 2013 - cell.com
In neurons, the distinct molecular composition of axons and dendrites is established through
polarized targeting mechanisms, but it is currently unclear how nonpolarized cargoes, such …
polarized targeting mechanisms, but it is currently unclear how nonpolarized cargoes, such …
Mixed microtubules steer dynein-driven cargo transport into dendrites
LC Kapitein, MA Schlager, M Kuijpers, PS Wulf… - Current biology, 2010 - cell.com
Background To establish and maintain their polarized morphology, neurons employ active
transport driven by molecular motors to sort cargo between axons and dendrites. However, …
transport driven by molecular motors to sort cargo between axons and dendrites. However, …
Optogenetic control of organelle transport and positioning
Proper positioning of organelles by cytoskeleton-based motor proteins underlies cellular events
such as signalling, polarization and growth 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 . For many organelles, …
such as signalling, polarization and growth 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 . For many organelles, …
Axon extension occurs independently of centrosomal microtubule nucleation
M Stiess, N Maghelli, LC Kapitein, S Gomis-Rüth… - Science, 2010 - science.org
Microtubules are polymeric protein structures and components of the cytoskeleton. Their
dynamic polymerization is important for diverse cellular functions. The centrosome is the …
dynamic polymerization is important for diverse cellular functions. The centrosome is the …