Microtubules are one of the major cytoskeletal components of neurons, essential for many
fundamental cellular and developmental processes, such as neuronal migration, polarity, and …

To establish and maintain their polarized morphology, neurons employ active transport driven
by cytoskeletal motor proteins to sort cargo between axons and dendrites. These motors …

Microtubules are polarized cytoskeletal filaments that serve as tracks for intracellular
transport and form a scaffold that positions organelles and other cellular components and …

During cell division, mitotic spindles are assembled by microtubule-based motor proteins 1 ,
2 . The bipolar organization of spindles is essential for proper segregation of chromosomes, …

Dendritic spines are the major sites of excitatory synaptic input, and their morphological
changes have been linked to learning and memory processes. Here, we report that growing …

Hypertrophic scarring and poor intrinsic axon growth capacity constitute major obstacles for
spinal cord repair. These processes are tightly regulated by microtubule dynamics. Here, …

In neurons, the distinct molecular composition of axons and dendrites is established through
polarized targeting mechanisms, but it is currently unclear how nonpolarized cargoes, such …

BACKGROUND: To establish and maintain their polarized morphology, neurons employ
active transport driven by molecular motors to sort cargo between axons and dendrites. …

Proper positioning of organelles by cytoskeleton-based motor proteins underlies cellular events
such as signalling, polarization and growth 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 . For many organelles, …

Microtubules are polymeric protein structures and components of the cytoskeleton. Their
dynamic polymerization is important for diverse cellular functions. The centrosome is the …