The effect of functional impairment of the renin-angiotensin system on the vasoconstriction
mediated by postsynaptic α 1 and α 2 -adrenoceptors in pithed normotensive rats was studied…

Inhibitors of the angiotensin I converting enzyme (captopril, enalapril) offer a new principle
in the drug treatment of hypertension and congestive heart failure. The present survey deals …

The present study characterized the effects of sodium nitroprusside (SNP) on the responsiveness
of pithed rats to pressor stimuli. Intravenous infusions of SNP produced a dose-related …

In the spinal pithed rat, DuP 753, 2-n-butyl-4-chloro-5-hydroxy methyl-i-[(2'-(i H-tetrazol-5-yI)
biphenyl4-yl) methyl] imidazole potassium salt, inhibited competitively the pressor response …

In pithed rats, but not in pithed cats, the α 2 ‐/dopamine agonist B‐HT 920 (10–300 μg kg −1
) increased cardiac output. The increase was inhibited by yohimbine (1 mg kg −1 ), but not …

1 The effects of angiotensin II (AII) and Bay K 8644 on responses to noradrenaline (NA)
mediated via postjunctional α 1 ‐ and/or α 2 ‐adrenoceptors have been compared in three …

1 The influence of angiotensin II (AII) on resting blood pressure and on sympathetic nerve‐mediated
pressor responses in the pithed rat was investigated either by inhibiting the renin‐…

The effects of chloroquine and some other antimalarials on the immune responses in experimental
animals have been examined. Chloroquine and quinine caused significant decrease …

Alpha-adrenoceptors are present on the varicosity membrane of noradrenergic nerve
endings where they participate in modulation of noradrenaline release. Activation of these so-…