Effect of converting enzyme inhibition and angiotensin receptor blockade on the vasoconstriction mediated by α1 and α2 stimulation in pithed normotensive rats

A De Jonge, JTA Knape, JCA Van Meel… - Naunyn-Schmiedeberg's …, 1982 - Springer
The effect of functional impairment of the renin-angiotensin system on the vasoconstriction
mediated by postsynaptic α 1 and α 2 -adrenoceptors in pithed normotensive rats was studied…

Inhibitors of the angiotensin I converting enzyme as antihypertensive drugs

PA Van Zwieten, A De Jonge, P Timmermans - Pharmaceutisch Weekblad, 1983 - Springer
Inhibitors of the angiotensin I converting enzyme (captopril, enalapril) offer a new principle
in the drug treatment of hypertension and congestive heart failure. The present survey deals …

Attenuation of the pressor activity of endogenous vasoconstrictors by sodium nitroprusside in the pithed rat

RR Vollmer, EM Strieker, SJ Fluharty - Clinical and Experimental …, 1989 - Taylor & Francis
The present study characterized the effects of sodium nitroprusside (SNP) on the responsiveness
of pithed rats to pressor stimuli. Intravenous infusions of SNP produced a dose-related …

Effect of chloroquine and some other antimalarials on the immune mechanism in experimental animals

SK Bhattacharya, CR Pillai, M Mathur… - Journal of pharmacy …, 1984 - academic.oup.com
The effects of chloroquine and some other antimalarials on the immune responses in experimental
animals have been examined. Chloroquine and quinine caused significant decrease …

The influence of α1‐ and α2‐adrenoceptor agonists on cardiac output in rats and cats

HO Kalkman, MJMC Thoolen… - Journal of pharmacy …, 1984 - Wiley Online Library
In pithed rats, but not in pithed cats, the α 2 ‐/dopamine agonist B‐HT 920 (10–300 μg kg −1
) increased cardiac output. The increase was inhibited by yohimbine (1 mg kg −1 ), but not …

Interactions between angiotensin II, sympathetic nerve‐mediated pressor response and cyclo‐oxygenase products in the pithed rat

TL Grant, JC McGrath - British journal of pharmacology, 1988 - Wiley Online Library
1 The influence of angiotensin II (AII) on resting blood pressure and on sympathetic nerve‐mediated
pressor responses in the pithed rat was investigated either by inhibiting the renin‐…

A comparison of the effects of angiotensin II and Bay K 8644 on responses to noradrenaline mediated via postjunctional α1‐and α2‐adrenoceptors in rabbit isolated …

WR Dunn, CJ Daly, JC McGrath… - British journal of …, 1991 - Wiley Online Library
1 The effects of angiotensin II (AII) and Bay K 8644 on responses to noradrenaline (NA)
mediated via postjunctional α 1 ‐ and/or α 2 ‐adrenoceptors have been compared in three …

[PDF][PDF] Nonpeptide angiotensin II receptor antagonists. VIII. Characterization of functional antagonism displayed by DuP 753, an orally active antihypertensive agent.

PC Wong, WA Price, AT Chiu, JV Duncia… - … of Pharmacology and …, 1990 - Citeseer
In the spinal pithed rat, DuP 753, 2-n-butyl-4-chloro-5-hydroxy methyl-i-[(2'-(i H-tetrazol-5-yI)
biphenyl4-yl) methyl] imidazole potassium salt, inhibited competitively the pressor response …

[CITAAT][C] Van zwieten, PA,(1982). Effect of converting enzyme inhibition and angiotensin receptor blockade on the vasoconstriction mediated by α1 and α2 …

A De Jonge, JTA Knape, B Wilffert, HO Kalkman… - Arch. Pharmacol

[CITAAT][C] Effect of converting enzyme inhibition and angiotensin receptor blockade on the vasoconstriction mediated by a, and a2-a (lrenoceptor stimulation in pithed …

A De Jonge, JTA Knape, JCA Van Meel - Naunyn Schmiedebergs Arch Pharmacol, 1982