Maintenance treatment with capecitabine and bevacizumab versus observation after induction treatment with chemotherapy and bevacizumab in metastatic colorectal …
M Koopman, LHJ Simkens, AJ Ten Tije, GJ Creemers… - 2013 - ascopubs.org
3502 Background: The optimal duration of chemotherapy and bevacizumab in mCRC is not
well established. The CAIRO3 study investigated the efficacy of maintenance treatment with …
well established. The CAIRO3 study investigated the efficacy of maintenance treatment with …
Clinical relevance of DPYD variants c. 1679T> G, c. 1236G> A/HapB3, and c. 1601G> A as predictors of severe fluoropyrimidine-associated toxicity: a systematic …
D Meulendijks, LM Henricks, GS Sonke… - The Lancet …, 2015 - thelancet.com
Background The best-known cause of intolerance to fluoropyrimidines is dihydropyrimidine
dehydrogenase (DPD) deficiency, which can result from deleterious polymorphisms in the …
dehydrogenase (DPD) deficiency, which can result from deleterious polymorphisms in the …
Powder metallurgy of titanium–past, present, and future
Powder metallurgy (PM) of titanium is a potentially cost-effective alternative to conventional
wrought titanium. This article examines both traditional and emerging technologies, including …
wrought titanium. This article examines both traditional and emerging technologies, including …
From tumour heterogeneity to advances in precision treatment of colorectal cancer
CJA Punt, M Koopman, L Vermeulen - Nature reviews Clinical oncology, 2017 - nature.com
In recent years, the high heterogeneity of colorectal cancer (CRC) has become evident. Hence,
biomarkers need to be developed that enable the stratification of patients with CRC into …
biomarkers need to be developed that enable the stratification of patients with CRC into …
Effectiveness of pulmonary rehabilitation in patients with chronic obstructive pulmonary disease with different degrees of static lung hyperinflation
MJ Vanfleteren, M Koopman, MA Spruit… - Archives of Physical …, 2018 - Elsevier
Objective To evaluate the effect of pulmonary rehabilitation (PR) on exercise performance
and quality of life in patients with chronic obstructive pulmonary disease (COPD) with different …
and quality of life in patients with chronic obstructive pulmonary disease (COPD) with different …
[BOEK][B] Diep leren: praktische handreikingen voor het bevorderen van diep leren bij leerlingen in het voortgezet onderwijs
M Koopman - 2017 - research.tue.nl
Hoe zorgen we ervoor dat leerlingen goed worden voorbereid op hun toekomst? Deze
vraag houdt leraren, scholen en beleidsmakers bezig. Veel scholen willen een stap zetten …
vraag houdt leraren, scholen en beleidsmakers bezig. Veel scholen willen een stap zetten …
[HTML][HTML] Deficient mismatch repair system in patients with sporadic advanced colorectal cancer
M Koopman, GAM Kortman, L Mekenkamp… - British journal of …, 2009 - nature.com
A deficient mismatch repair system (dMMR) is present in 10–20% of patients with sporadic
colorectal cancer (CRC) and is associated with a favourable prognosis in early stage disease. …
colorectal cancer (CRC) and is associated with a favourable prognosis in early stage disease. …
[HTML][HTML] Chemotherapy, bevacizumab, and cetuximab in metastatic colorectal cancer
J Tol, M Koopman, A Cats, CJ Rodenburg… - … England Journal of …, 2009 - Mass Medical Soc
Background Fluoropyrimidine-based chemotherapy plus the anti–vascular endothelial
growth factor (VEGF) antibody bevacizumab is standard first-line treatment for metastatic …
growth factor (VEGF) antibody bevacizumab is standard first-line treatment for metastatic …
[HTML][HTML] Treatment of venous thrombosis with intravenous unfractionated heparin administered in the hospital as compared with subcutaneous low-molecular-weight …
MMW Koopman, P Prandoni, F Piovella… - … England Journal of …, 1996 - Mass Medical Soc
Background An intravenous course of standard (unfractionated) heparin with the dose
adjusted to prolong the activated partial-thromboplastin time to a desired length is the standard …
adjusted to prolong the activated partial-thromboplastin time to a desired length is the standard …
Sequential versus combination chemotherapy with capecitabine, irinotecan, and oxaliplatin in advanced colorectal cancer (CAIRO): a phase III randomised controlled …
M Koopman, NF Antonini, J Douma, J Wals… - The Lancet, 2007 - thelancet.com
Background The optimum use of cytotoxic drugs for advanced colorectal cancer has not
been defined. Our aim was to investigate whether combination treatment is better than …
been defined. Our aim was to investigate whether combination treatment is better than …