Aspartame is a methyl ester of a dipeptide used as a synthetic nonnutritive sweetener in
over 90 countries worldwide in over 6000 products. The purpose of this investigation was to …

Exposure assessment is one of the key parts of the risk assessment process. Only intake of
toxicologically significant amounts can lead to adverse health effects even for a relatively …

Reviews on the safety of glyphosate and Roundup herbicide that have been conducted by
several regulatory agencies and scientific institutions worldwide have concluded that there is …

The threshold of toxicological concern (TTC) has been used for the safety assessment of
packaging migrants and flavouring agents that occur in food. The approach compares the …

Rats (Rattus norvegicus) emit a variety of ultrasonic vocalizations throughout their lifespan
that reflect different forms of emotional arousal and accompanying affective states. In this study…

Fifty-kHz ultrasonic vocalizations have been proposed to reflect a positive appetitive affective
state in rats, being consistently linked to the positive appetitive behavior. In the first study, …

The concept that “safe levels of exposure” for humans can be identified for individual chemicals
is central to the risk assessment of compounds with known toxicological profiles. The …

The threshold of toxicological concern (TTC) is a pragmatic risk assessment tool that is based
on the principle of establishing a human exposure threshold value for all chemicals, below …

Sodium salicylate, an anti-inflammatory agent, was examined for its effects on the heat shock
response in cultured human cells. Salicylate activation of DNA binding by the heat shock …

When it comes to the production and distribution of mass culture, no country in modern times
has come close to rivaling the success of America. From blue jeans in central Europe to …