Importance The incidence of early-onset colorectal cancer (younger than 50 years) is rising
globally, the reasons for which are unclear. It appears to represent a unique disease process …

A number of risk factors based upon mostly retrospective surgical data, have been formulated
in order to identify impending pathological fractures of the femur from low-risk metastases. …

Enchondromatosis is a rare, heterogeneous skeletal disorder in which patients have multiple
enchondromas. Enchondromas are benign hyaline cartilage forming tumors in the medulla …

Objective There are insufficient data on the effects of long‐term intensive exercise in patients
with rheumatoid arthritis (RA). We undertook this randomized, controlled, multicenter trial to …

Objective To develop a scoring system for quantifying osteoarthritic changes of the knee as
identified by magnetic resonance (MR) imaging, and to determine its inter- and intra-…

The data on 98 new patients with osteoblastoma were studied. The clinical features of pain,
scoliosis, and neurologic deficit were largely consistent with those in previous reports. …

Osteoarthritis [MIM 165720] is a common late-onset articular joint disease for which no
pharmaceutical intervention is available to attenuate the cartilage degeneration. To identify a new …

Background The femoral nerve block (FNB) may be used for analgesia in hip fracture
surgery. The pericapsular nerve group (PENG) block is a novel regional technique and may …

The purpose of this study was to evaluate clinical symptoms and radiographic features that
allow radiologists to differentiate between enchondroma and central grade 1 chondrosarcoma…

Objective: The aim of this study was to compare open esophagectomy (OE) with minimally
invasive esophagectomy (MIE) in a population-based setting. Background: Randomized …