[HTML][HTML] Coxsackievirus protein 2B modifies endoplasmic reticulum membrane and plasma membrane permeability and facilitates virus release

FJM van Kuppeveld, JGJ Hoenderop… - The EMBO …, 1997 - embopress.org
Digital‐imaging microscopy was performed to study the effect of Coxsackie B3 virus
infection on the cytosolic free Ca 2+ concentration and the Ca 2+ content of the endoplasmic …

Structure–function analysis of coxsackie B3 virus protein 2B

FJM VAN KUPPEVELD, WJG MELCHERS… - Virology, 1997 - Elsevier
Expression of poliovirus protein 2B in mammalian cells inhibits protein secretion and
increases the susceptibility of the cells to hygromycin B, consistent with the increase in plasma …

Multimerization reactions of coxsackievirus proteins 2B, 2C and 2BC: a mammalian two-hybrid analysis

AS de Jong, IWJ Schrama… - Journal of general …, 2002 - microbiologyresearch.org
Recently, homomultimerization and heteromultimerization reactions of the poliovirus P2 region
proteins were investigated using a yeast two-hybrid approach (Cuconati et al., Journal of …

Picornavirus security proteins promote the release of extracellular vesicle enclosed viruses via the modulation of host kinases

KAY Defourny, X Pei, FJM van Kuppeveld… - PLoS …, 2024 - journals.plos.org
The discovery that extracellular vesicles (EVs) serve as carriers of virus particles calls for a
reevaluation of the release strategies of non-enveloped viruses. Little is currently known …

Tyrphostin AG1478 inhibits encephalomyocarditis virus and hepatitis C virus by targeting phosphatidylinositol 4-kinase IIIα

CM Dorobantu, C Harak, R Klein… - Antimicrobial agents …, 2016 - Am Soc Microbiol
Encephalomyocarditis virus (EMCV), like hepatitis C virus (HCV), requires phosphatidylinositol
4-kinase IIIα (PI4KA) for genome replication. Here, we demonstrate that tyrphostin …

Chimeric coxsackie B3 virus genomes that express hybrid coxsackievirus-poliovirus 2B proteins: functional dissection of structural domains involved in RNA …

FJM van Kuppeveld… - Journal of general …, 1997 - microbiologyresearch.org
The 2B proteins of coxsackievirus and poliovirus (PV) share significant structural similarity
and exhibit similar biochemical activities, namely inhibition of protein secretion and …

Prevalence of xenotropic murine leukaemia virus-related virus in patients with chronic fatigue syndrome in the Netherlands: retrospective analysis of samples from an …

FJM Kuppeveld, AS Jong, KH Lanke, GW Verhaegh… - 2010 - cabidigitallibrary.org
Objective: The presence of the retrovirus xenotropic murine leukaemia virus-related virus (XMRV)
has been reported in peripheral blood mononuclear cells of patients with chronic …

[PDF][PDF] No evidence of mycoplasmas in peripheral blood mononuclear cell fraction of HIV-infected patients.

FJM van Kuppeveld, WJG Melchers, J Kissing, J Logt… - 1994 - repository.ubn.ru.nl
In this study, the prevalence of mycoplasmas in peripheral blood mononuclear cells (PBMC)
from HIV-infected individuals was investigated using a mycoplasma genusspecific PCR …

A single point mutation creating a furin cleavage site in the spike protein renders porcine epidemic diarrhea coronavirus trypsin independent for cell entry and fusion.

LWT Li WenTao, O Wicht, FJM Kuppeveld… - 2015 - cabidigitallibrary.org
The emerging porcine epidemic diarrhea virus (PEDV) requires trypsin supplementation to
activate its S protein for membrane fusion and virus propagation in cell culture. By …

Identification of sialic acid-binding function for the Middle East respiratory syndrome coronavirus spike glycoprotein.

LWT Li WenTao, RJG Hulswit, I Widjaja, VS Raj… - 2017 - cabidigitallibrary.org
Middle East respiratory syndrome coronavirus (MERS-CoV) targets the epithelial cells of the
respiratory tract both in humans and in its natural host, the dromedary camel. Virion …