[CITAAT][C] DNA repair, cancer and aging.
JHJ Hoeijmakers, G Weeda, GTJ van der Horst, J Boer… - New England Journal of …, 1998
[PDF][PDF] Crystallization of the xeroderma pigmentosum group F endonuclease from Aeropyrum pernix
J Lally, M Newman, J Murray-Rust… - … Section D: Biological …, 2004 - journals.iucr.org
The xeroderma pigmentosa group F protein (XPF) is a founding member of a family of 3′-flap
endonucleases that play an essential role in nucleotide-excision repair, DNA replication …
endonucleases that play an essential role in nucleotide-excision repair, DNA replication …
Expression of genes involved in nucleotide excision repair and sensitivity to cisplatin and melphalan in human cancer cell lines
G Damia, G Guidi, M D'Incalci - European Journal of Cancer, 1998 - Elsevier
DNA repair has been proposed to be an important determinant of cancer cell sensitivity to
alkylating agents and cisplatin (DDP). Nucleotide excision repair (NER), which represents one …
alkylating agents and cisplatin (DDP). Nucleotide excision repair (NER), which represents one …
Estudos de complementação fenotípica do mutante pso2-1 de Saccharomyces cerevisiae pelos genes uvr de Escherichia coli
CF Lenzi - 2005 - lume.ufrgs.br
O mecanismo de reparação de DNA por excisão de nucleotídeos (NER) é o mais universal
e conservado sistema de reparação encontrado em organismos procarióticos e eucarióticos. …
e conservado sistema de reparação encontrado em organismos procarióticos e eucarióticos. …
O mutante pso9-1 de Saccharomyces cerevisiae, sensível a psoralenos fotoativados, contém um alelo mutante do gene MEC3 envolvido em checkpoint
JM Cardone - 2002 - lume.ufrgs.br
Análises de complementação do mutante pso9-1, sensível a psoralenos mono- e bifuncionais
fotoativados, UV254nm e nitrosoguanidina, com os mutantes pso1 a pso8, confirmou que …
fotoativados, UV254nm e nitrosoguanidina, com os mutantes pso1 a pso8, confirmou que …
The role of Transcription Factor IIH complex in nucleotide excision repair
A Hoag, M Duan, P Mao - Environmental and molecular …, 2024 - Wiley Online Library
DNA damage occurs throughout life from a variety of sources, and it is imperative to repair
damage in a timely manner to maintain genome stability. Thus, DNA repair mechanisms are a …
damage in a timely manner to maintain genome stability. Thus, DNA repair mechanisms are a …
The role of DNA repair in development
ET Snow - Reproductive Toxicology, 1997 - Elsevier
Several pathways of DNA repair are essential for maintaining genomic integrity in mammalian
cells. Mismatch repair is the final line of defense against polymerase errors during normal …
cells. Mismatch repair is the final line of defense against polymerase errors during normal …
[BOEK][B] Functional analysis of the MMS19 gene in Carica papaya
JA Trujillo - 2015 - search.proquest.com
All organisms face DNA-damaging radiation in the form of UV light and must have mechanisms
to repair or undo damage. Plants being stationary organisms must cope with damaging …
to repair or undo damage. Plants being stationary organisms must cope with damaging …
A humán Spartan szerepe a DNS− fehérje keresztkötések eltávolításában
E Zsigmond - 2021 - search.proquest.com
Sejtjeink folyamatosan különböző DNS károsító hatásoknak vannak kitéve, mint például az
UV sugárzás vagy különböző vegyületek. De nem csak külső tényezők károsíthatják DNS-…
UV sugárzás vagy különböző vegyületek. De nem csak külső tényezők károsíthatják DNS-…
Variant requirements for DNA repair proteins in cancer cell lines that use alternative lengthening of telomere mechanisms of elongation
AR Martinez - 2016 - rave.ohiolink.edu
The human genome relies on DNA repair proteins and the telomere to maintain genome
stability. Genome instability is recognized as a hallmark of cancer, as is limitless replicative …
stability. Genome instability is recognized as a hallmark of cancer, as is limitless replicative …